An ethological description of mother-infant interaction suggests that it was adaptive during human evolution. From their early weeks, infants universally respond to certain affect-laden elements of maternal communication that can be called "proto-aesthetic." I hypothesize that these capacities and receptivities, which evolved from about 1.7 million years ago to enable mother-infant bonding, became a reservoir of affective mechanisms that could be used subsequently by ancestral humans when they first began to "artify"-that is, when they invented the "arts" as vehicles of ceremonial religious experience. The ethological, evolutionary, and cross-cultural foundations of the Artification Hypothesis challenge current influential ideas in cognitive science, evolutionary aesthetics, and neuroaesthetics about human aesthetic capacities and behavior. The hypothesis offers a broader and deeper view to these fields by emphasizing preverbal, presymbolic, pancultural, cross-modal, supra-modal, participative, temporally organized, affective, and affinitive aspects of aesthetic cognition and behavior. It additionally proposes that artifying is an unrecognized but vital evolved component of human nature. CORRESPONDENCE: Ellen Dissanayake.