PHS Guideline for Reducing Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Transmission through Organ Transplantation

Seem, Debbie; Lee, Ingi; Umscheid, Craig A.; Kuehnert, Matthew J.

doi:10.1177/003335491312800403

Cited by 222 publications

(227 citation statements)

References 184 publications

(744 reference statements)

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“…Two patients died, and two others suffered graft loss. In 2009, a living kidney donor had a negative serum HIV antibody test 79 days prior to [13].…”

Section: Epidemiology and Outcome By Organismmentioning

confidence: 99%

Donor-Derived Infection: Epidemiology and Outcomes

Kaul

2012

Curr Infect Dis Rep

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Over the past decade, the solid organ transplant community has focused increased attention on unexpected transmission of infectious pathogens from organ donor to recipient. While unexpected donor-derived infections are relatively uncommon, recent cases of transmission of human immunodeficiency virus (HIV) and hepatitis C to multiple recipients, as well as transmission of HIV from a living donor, have further increased interest in improving the safety of solid organ transplantation. This article will review the epidemiology and outcomes associated with unexpected donor-derived infection. Furthermore, the reporting and patient safety process will be discussed, as will preventative measures that can reduce the burden of donor-derived infection.

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“…Two patients died, and two others suffered graft loss. In 2009, a living kidney donor had a negative serum HIV antibody test 79 days prior to [13].…”

Section: Epidemiology and Outcome By Organismmentioning

confidence: 99%

Donor-Derived Infection: Epidemiology and Outcomes

Kaul

2012

Curr Infect Dis Rep

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“…Transplant professionals want to identify these donors because these infections can be transmitted in the graft (6). For deceased donor organs, the United Network for Organ Sharing (UNOS)/Organ Procurement and Transplantation Network (OPTN) has a policy that requires that candidates be informed whether their deceased donor meets the Centers for Disease Control and Prevention increased risk classification for infection transmission (15.3 bullet 2), even if the donor tests negative (7).…”

Section: Introductionmentioning

confidence: 99%

Disclosing Health and Health Behavior Information between Living Donors and Their Recipients

Mataya¹,

Meadow²,

Thistlethwaite

et al. 2015

Clinical Journal of the American Society of Nephrology

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Background and objectives Living donor guidelines-both national and international-either do not address or are vague about what information can be shared between prospective living donors and transplant candidates, as well as when to make such disclosures and who should make them. This study explored the attitudes of donors and recipients regarding how much information they believe should be shared.Design, setting, participants, & measurements Two Email invitations were sent by the National Kidney Foundation (national headquarters) to its Email listservs, inviting members to participate in an online survey to assess the attitudes of kidney transplant stakeholders regarding the disclosure of health and health risk behavior information.Results From approximately 4200 unique Email addresses, 392 (9.3%) respondents completed part or all of the survey. The analyses were limited to the 236 respondents who self-identified as either donors (potential and actual, n=160) or recipients (candidates and actual, n=76). Overall, 79% (186 of 234) of respondents supported disclosure of general recipient health information that would affect post-transplant outcome to donors, and 88% (207 of 235) supported disclosure of general donor health information to recipients. Recipients and donors were also supportive of sharing donor and recipient information, particularly information relevant to graft and patient survival. There is some reticence, however, about sharing social information. The closer the relationship, the more information they are willing to share. Both donors and recipients wanted the transplant team involved in the information disclosure. Over three quarters of donors (79%) and recipients (78%) did not think the recipient had a right to know why a donor was excluded from donating.Conclusions Both donors and recipients want a significant amount of health information to be disclosed. The opinions of other stakeholders need to be surveyed to determine whether a revision of current policies and practices is warranted.

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“…Additionally, the same report stated "multiple sexual partners" are considered a risk factor for contracting other STIs such as HIV. The justification for this change was based on "different" or "undefined" thresholds (Seem et al 2011). Several of these reports do mention other risk factors and methods of prevention, such as use or lack of contraception and engaging in sexual behavior with an infected partner, but the ambiguity and inconsistency relating to the number of sexual partners is relative aspect to this study.…”

Section: "Multiple or A High Number Of Sexual Partners"mentioning

confidence: 99%

“…One can conclude that an average male is always at high risk for STls and HIV and the average female is not far behind. In the report on organ donation protocol, the CDC&P suggests, based what they call "low equality evidence," that after more than two sexual partners per year a person is essentially promiscuous and their body is unhealthy (Seem et al 2011). Essentially, the CDC&P does not take into account the sexual history of the partners one has.…”

Section: Sexual Double Standardmentioning

confidence: 99%

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PHS Guideline for Reducing Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Transmission through Organ Transplantation

Cited by 222 publications

References 184 publications

Donor-Derived Infection: Epidemiology and Outcomes

Donor-Derived Infection: Epidemiology and Outcomes

Disclosing Health and Health Behavior Information between Living Donors and Their Recipients

"What do you mean I'm a slut?!?!" : deconstructing the definitions of promiscuity of the collective conscience using concepts from labeling theory and biopower."

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