Phthalates and organophosphorus insecticide residues in shrimp determined by liquid/gas chromatography–Tandem mass spectrometry and a health risk assessment

Chang, H.; Yang, Wei-Cheng; Xue, Yi-Jing; Tsai, Ming-Yang; Wang, Jiann-Hsiung; Chang, Geng-Ruei

doi:10.1016/j.marpolbul.2019.04.047

Cited by 20 publications

(43 citation statements)

References 27 publications

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“…The average EDI levels extrapolated from the average chlorpyrifos levels in Taiwanese women and men were 0.002 and 0.003 µg/kg body weight/day, respectively (Table 4). The EDI levels were noted to be substantially lower than the JECFA-recommended chlorpyrifos ADI level of 0.01 mg/kg (Table 4) [4,15]. Moreover, the EDI levels expressed as the percentages of the ADIs were 0.03% and 0.02% in men and women, respectively.…”

Section: Edi Levels Of Residues Of Organophosphorus Insecticides Ingementioning

confidence: 81%

“…Here, we adopted the analytical approach for sulfonamide residues suggested by the TFDA [16] and that for organophosphorus insecticide residues developed by the European Committee for Standardization, the QuEChERS (quick, easy, cheap, effective, rugged, and safe) method [4,21]-both of which are suitable for detecting trace chemical residues. For the validation of its analytic method, the TFDA [2,22] recommends an acceptable recovery rate of 70-120% [relative standard deviation (RSD) < 15%], 70-120% (RSD < 20%), and 50-125% (RSD < 35%) for chemical residues in food matrices detected in the 0.1-1, 0.001-0.01, and <0.001 mg/kg ranges, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…In all fish samples, 5.77% was the detection rate for all studied organophosphorus insecticide residues, with the highest rate being for chlorpyrifos (6.25%) in milk fish and perch samples, followed by tilapia samples (5.0%). During their aquaculture activities, some farmers in Taiwan apply organophosphorus insecticides for ectoparasite treatment [4]. Sun et al [35] reported an organophosphorus insecticide detection rate of 11.37% in 607 fish samples from traditional markets, regional supermarkets, fish markets, and fish farms in Taiwan over 2001-2003; however, over 2002-2004, the authors reported an organophosphorus insecticide detection rate of 16.83% (only chlorpyrifos) in 814 fish samples from Taiwan markets [36].…”

Section: Discussionmentioning

confidence: 99%

“…In Taiwan, more than 35 major and candidate aquatic species are commercially aquacultured [3]. Over 2010-2018, Taiwan's revenue derived from land aquaculture was up to US$1 billion on average [3]; in addition, during the 2010s, Taiwan's estimated annual land aquaculture production was 300,000 t [4]. Moreover, in Taiwan, major developments in aquaculture occurred over the 1960s to the 1990s [2], mainly because of the strong support of the government since the 1960s [5].…”

Section: Introductionmentioning

confidence: 99%

“…However, sulfonamides have several side effects; for example, they have been demonstrated to engender reduced filet palatability of aquacultured products, increased kidney damage and infertility risk, and physiological and immunological response disruptions [1,12]. Massive and repeated illegal use of organophosphorus insecticides to control parasitic diseases in aquacultured organisms has also been noted in Taiwan [4]; these insecticides mainly inhibit acetylcholinesterase activity and disrupt nerve function in humans [13].…”

Section: Introductionmentioning

confidence: 99%

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Analytical Detection of Sulfonamides and Organophosphorus Insecticide Residues in Fish in Taiwan

et al. 2020

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Exposure to residues of antibiotics (e.g., sulfonamides) and insecticides (e.g., organophosphorus insecticides) in aquacultured food can adversely affect humans and animals and thus affect public health globally. Here, using a validated method, we examined the levels of residues of 12 sulfonamides as well as 18 organophosphorus insecticides in aquacultured fish in Taiwan. A total of 52 fish samples (i.e., 20 tilapia, 16 milk fish, and 16 perch samples) were obtained from Taiwanese aquafarms from June 2018 to October 2019. We detected 0.02 and 0.03 mg/kg of sulfamethazine (a sulfonamide) in one tilapia and one milk fish, respectively, and 0.02, 0.05, and 0.03 mg/kg of chlorpyrifos (an organophosphorus insecticide) in one tilapia, one milk fish, and one perch, respectively; thus, among the samples, 3.85% and 5.77% contained sulfonamides and organophosphorus insecticide residues, respectively. Furthermore, we assessed human health risk based on the estimated daily intakes (EDIs) of these residues: EDIs of sulfonamide and organophosphorus insecticide residues were <1.0% of the acceptable daily intake recommended by the Joint Food and Agriculture Organization of the United Nations/World Health Organization Expert Committee on Food Additives. The risk of exposure to sulfonamide and organophosphorus insecticide residue by consuming aquacultured fish in Taiwan was thus negligible, signifying no immediate health risk related to the consumption of fish. Our findings can constitute a reference in efforts geared toward ensuring food safety and monitoring veterinary drug and insecticide residue levels in aquacultured organisms. Residue levels in fish must be continually monitored to further determine possible effects of these residues on human health.

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Section: Edi Levels Of Residues Of Organophosphorus Insecticides Ingementioning

confidence: 81%