pHyloGASTRO in the Treatment of Equine Gastric Ulcer Lesions

Bonelli, Francesca; Busechian, Sara; Meucci, Valentina; Caporrino, Giusy; Briganti, Angela; Rueca, Fabrizio; Zappulla, Francesco; Ferini, Ersilia; Ghiandai, Luana; Sgorbini, Micaela

doi:10.1016/j.jevs.2016.06.069

Cited by 14 publications

(10 citation statements)

References 33 publications

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“…They are important for the tourist industry and recently have become popular as pets (Thiemann and Rickards, 2013;El-Shafaey et al, 2017;Salem et al, 2018). The scientific literature has shown increased interest in their welfare (Rota et al, 2018), in donkeys' infectious diseases (Laus et al, 2015;Barrandeguy and Carossino, 2018;Sgorbini et al, 2018), alternative therapies (Bonelli et al, 2016a), and in specific diagnostic criteria and reference values in adults (Meucci et al, 2015;Sgorbini et al, 2017;Bonelli et al, 2019), pregnant and lactating jennies (Crisci et al, 2014;Bonelli et al, 2016b;Carluccio et al, 2016), and donkey foals (Sgorbini et al, 2013;Veronesi et al, 2014;Carluccio et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Radiographic parameters of the digit in a cohort population of Amiata donkeys

Nocera¹,

Aliboni²,

Puccinelli³

et al. 2021

Open Vet J.

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Background: The most common musculoskeletal conditions reported in donkeys are related to the foot. Radiographic examinations are clinically important in the diagnosis of foot abnormalities and are commonly used. However, few studies have been conducted to establish the normal radiographic appearance of a donkey’s foot. Aim: To determine the radiographic features of the front digit in healthy Amiata donkeys. Methods: Radiographic examinations were performed on 56 forefeet of 28 Amiata donkeys. Three radiographic views of each front foot were taken: lateromedial, dorsopalmar and dorso 65°proximal/palmarodistal oblique. Seventeen angular and linear radiographic parameters and the crena solearis were evaluated in all forefeet, and 18 morphometric parameters were evaluated in 16 out of 56 forefeet. Statistical analysis was carried out on all the measures assessed. Results: The radiographic appearance of the forefoot was ascertained, and data were reported as median ± standard error, minimum and maximum values. No statistical differences were obtained between the right and left forefeet. Conclusion: The normal baseline parameters of the forefeet of Amiata donkeys were recorded and described and compared with other donkey breeds and horses. The findings highlighted that the donkey breed affects the radiographic parameters of the digit.

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Section: Introductionmentioning

confidence: 99%

Radiographic parameters of the digit in a cohort population of Amiata donkeys

Nocera¹,

Aliboni²,

Puccinelli³

et al. 2021

Open Vet J.

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“…Various formulations of polyphenols, such as bacteriostatic, anti-clostridial and astringent, have been tested, especially in monogastric nutrition [4][5][6][7]. Some phytotherapic options have been evaluated for gastrointestinal diseases, such as gastric ulcers and gastric lesions, in rats, piglets, horses, and calves [8][9][10]. Pomegranate-residue supplements have been used in neonatal calves affected by Cryptosporidium parvum, resulting in a reduction in the fecal oocyst count, as well as in intensity and duration of diarrhea [11].…”

Section: Introductionmentioning

confidence: 99%

Oral administration of chestnut tannins to reduce the duration of neonatal calf diarrhea

et al. 2018

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BackgroundNeonatal calf diarrhea is generally caused by infectious agents and is a very common disease in bovine practice, leading to substantial economic losses. Tannins are known for their astringent and anti-inflammatory properties in the gastro-enteric tract. The aim of this study was to evaluate the effect of the oral administration of chestnut tannins (Castanea sativa Mill.) in order to reduce the duration of calf neonatal diarrhea. Twenty-four Italian Friesian calves affected by neonatal diarrhea were included. The duration of the diarrheic episode (DDE) was recorded and the animals were divided into a control group (C), which received Effydral® in 2 l of warm water, and a tannin-treated group (T), which received Effydral® in 2 l of warm water plus 10 g of extract of chestnut tannins powder. A Mann-Whitney test was performed to verify differences for the DDE values between the two groups.ResultsThe DDE was significantly higher in group C than in group T (p = 0.02), resulting in 10.1 ± 3.2 and 6.6 ± 3.8 days, respectively.ConclusionsPhytotherapic treatments for various diseases have become more common both in human and in veterinary medicine, in order to reduce the presence of antibiotic molecules in the food chain and in the environment. Administration of tannins in calves with diarrhea seemed to shorten the DDE in T by almost 4 days compared to C, suggesting an effective astringent action of chestnut tannins in the calf, as already reported in humans. The use of chestnut tannins in calves could represent an effective, low-impact treatment for neonatal diarrhea.

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“…In this study, the healing rate of the FFD group horses was higher than in similar studies (Bonelli et al 2016). We only used horses with EGUS grade 2 or higher because of the higher clinical relevance of the disease at a severity score ≥ 2.…”

Section: Groupmentioning

confidence: 82%

“…But there are few studies on the preventive measures, especially the influence of feeding. The research for the methods to treat or prevent gastric ulcers effectively, without using expensive pharmaceutical agents is a new trend in veterinary medicine (Bonelli et al 2016, Sutton 2016. To meet this growing need, this study aimed to evaluate the effectiveness of a change in the feeding regime as a part of the treatment of EGUS in adult horses.…”

Section: Discussionmentioning

confidence: 99%

The impact of feeding a high-fibre and high-fat concentrated diet on the recovery of horses suffering from gastric ulcers

Böhm¹,

Mitterer²,

Iben³

2018

PHK

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The objective of this study was to find out whether a change from a grain-rich concentrated feed to a grain-free, fibre-and fatenriched concentrated diet (FFD), leads to an improvement in gastric ulcers in horses. The experiment was conducted as a prospective experimental study. Thirty-four adult horses with gastric lesions-six mares and 28 geldings-fulfilled the inclusion criteria of this study. The average age was 11± 4 (mean ± SD) years and the horses weighed between 358 kg and 697 kg. Twenty horses were fed the FFD, while 14 horses were controls (C) and received their usual concentrated feed. Each horse underwent gastroscopy twice, at an interval of eight weeks. An independent evaluation of the examination and the scoring of the lesions, using the Equine Gastric Ulcer Council 0-4 scoring system for equine gastric ulcer syndrome (EGUS), was performed by an experienced gastroscopist. The horses with EGUS scores ≥ 3 received additional omeprazole at the recommended dosage for 14 days. The horses of the FFD group were adapted to the new diet whereas the control group received their usual concentrate. In the control group, only the amounts of hay and concentrate were adjusted to the requirement of the respective horse. After the change of the ration, the starch intake (FFD 0.09 ± 0.05 g/kg BW; C 1.38 ± 0.62 g/kg BW) was significantly different. However, there was no difference concerning the hay intake (FFD 21.2 ± 3.5 g/kg BW/day; C 23.3 ± 5.1 g/kg BW/day), the Ca intake (FFD 0.129± 0.034 g/kg BW/day; C 0.112 ± 0.019 g/kg BW/day), the Mg intake (FFD 0.042 ± 0.009 g/kg BW/day; C 0.042 ± 0.011g/kg BW/day) or the intake of the praecaecal digestible protein (FFD 1.42 ± 0.38 g/kg BW/day; C 1.58 ± 0.39 g/kg BW/day). The prevalence and severity of the mucosal lesions significantly decreased in the FFD group (p<0.001). No significant correlation between the EGUS and the other risk factors, such as workload, behaviour or typical symptoms was found in this study. The change of the concentrated feed to FFD improved the gastric ulcerations in both squamous and glandular mucosa.

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pHyloGASTRO in the Treatment of Equine Gastric Ulcer Lesions

Cited by 14 publications

References 33 publications

Radiographic parameters of the digit in a cohort population of Amiata donkeys

Radiographic parameters of the digit in a cohort population of Amiata donkeys

Oral administration of chestnut tannins to reduce the duration of neonatal calf diarrhea

The impact of feeding a high-fibre and high-fat concentrated diet on the recovery of horses suffering from gastric ulcers

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