Phylogenetic analysis of the first four SARS‐CoV‐2 cases in Chile

Abstract

The current pandemic caused by the new coronavirus is a worldwide public health concern. To aboard this emergency, and like never before, scientific groups around the world have been working in a fast and coordinated way to get the maximum of information about this virus when it has been almost 3 months since the first cases ORCID Andrés E. Castillo

Effects of SARS-CoV-2 Mutations on Protein Structures and Intraviral Protein-Protein Interactions

“…In the last several months, residents in more than 180 countries/regions have been affected by SARS-CoV-2, and the emergence of mutations might already make important contributions to virus adaption to new environments and selective pressures, which in turn can impact transmissibility, pathogenesis and immunogenicity of SARS-CoV-2 [33]. It has been reported that variant SARS-CoV-2 genomes occurred in different areas [34][35][36][37][38]. Our results also showed that some mutations were widely distributed, and their occurrence rates had different dynamic fluctuations.…”

Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile

“…We have already published the phylogenetic analysis of the first four genomes detected in Chile that revealed the two variants derived from strains present mainly in Europe (16).…”

Tracing New Clinical Manifestations in Patients with COVID-19 in Chile and Its Potential Relationship with the SARS-CoV-2 Divergence

“…The S type, which is evolutionarily older and less aggressive, might have increased in relative frequency due to relatively weaker selective pressure [32]. In a recent study from Chile on the first four cases of SARS-CoV-2/COVID-19 in Chile, authors suggest that at least two different viral variants entered into the country, from Europe and Asia [33].…”