“…A single A2189T mutation, associated with hepatocellular carcinoma, was found in the PC/core region ( 2 , 5 ). Two important amino acid changes, A128V and 144E, were found, which are associated with vaccine and/or diagnostic escape phenomena ( 6 , 7 ). The isolate was identified as genotype D and evolutionarily related to HBV strains from Bangladesh, Italy, and Estonia ( Fig.…”