Phylogenetic and Geographic Relationships of Severe Fever With Thrombocytopenia Syndrome Virus in China, South Korea, and Japan

Abstract

Two clades of SFTSV may have evolved separately over time. On rare occasions, the viruses were transmitted overseas to the region in which viruses of the other clade were prevalent.

Establishment of Subclones of the Severe Fever with Thrombocytopenia Syndrome Virus YG1 Strain Selected Using Low pH-Dependent Cell Fusion Activity

“…However, it is unclear whether the subclones existed in the original patient material or appeared through passages in Vero E6 cells. Yoshikawa et al reported the nucleotide sequences of the YG1 virus isolated from Vero cells and registered them in the DNA database of Japan (DDBJ) (19). These submitted sequences are identical to those of E3.…”

The emergence and cross species transmission of newly discovered tick-borne Bunyavirus in China

“…To date, all known HYSVs identified in China can be classified into six lineages [14,16,18] and there are three lineages of HYSVs in Japan [19 ] with the third lineage from Japan closely related to the HYSVs from Zhejiang Province, China. These data suggest that these viruses have a recent common ancestor, likely due to migration of their hosts.…”

Investigation of Severe Fever with Thrombocytopenia Syndrome Virus Antibody among Domestic Bovines Transported to Slaughterhouse in Shimane Prefecture, Japan

“…In Japan, 163 patients with SFTS were identified between the autumn of 2012 and October 2015, with most cases occurring in the western part of Japan, including Shimane Prefecture, located in Chugoku region of Honshu island (7)(8)(9).…”