Phylogenetic relationships of Strongyloides species in carnivore hosts

Ko, Phoo Pwint; Suzuki, Kazuo; Canales, Marco; Aung, Myo Pa Pa Thet Hnin Htwe; Htike, Wah Win; Yoshida, Ayako; Montes, Martín; Morishita, Kazuhiro; Gotuzzo, Eduardo; Maruyama, Haruhiko; Nagayasu, Eiji

doi:10.1016/j.parint.2020.102151

Cited by 21 publications

(21 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, molecular phylogeny approaches based on the mitochondria and genome markers in S. stercoralis were used to understand microevolution and the phylo-geographical gene flow of S. stercoralis haplotypes among various endemic areas of the world [9][10][11][12]. Nagayasu et al [10] suggested that 2 distinct genetic lineages of S. stercoralis, referred to as Clade I and Clade II, were detected after 571 isolates were genetically analyzed.…”

mentioning

confidence: 99%

Phylogenetic Positioning of a Strongyloides stercoralis Isolate Recovered from a Korean Patient and Comparison with Other Asian Isolates

et al. 2020

View full text Add to dashboard Cite

Strongyloidiasis is caused by Strongyloides stercoralis and is one of the most neglected tropical diseases in tropical and subtropical regions. Although several strongyloidiasis cases have been reported in Korea, genetic analysis of Korean isolates is still incomplete. In this study, a parasite was isolated from a 61-year-old man diagnosed with strongyloidiasis during the treatment of lymphoma on his retroperitoneal lymph node. Diffuse symmetric wall thickening from the ascending to descending colon and a nematode-infected intestine was observed following microscopic examination. Genomic DNA was isolated from a patient tissue block, and S. stercoralis was identified by PCR and sequencing (18S rDNA). In order to determine phylogenetic location of a Korean isolate (named KS1), we analyzed cox1 gene (500-bp) and compared it with that from 47 previous S. stercoralis isolates (28 human isolates and 19 canid isolates) from Asian countries. Our results showed that phylogenetic tree could clearly be divided into 5 different groups according to hosts and regions. KS1 was most closely related with the Chinese isolates in terms of genetic distance.

show abstract

mentioning

confidence: 99%

Phylogenetic Positioning of a Strongyloides stercoralis Isolate Recovered from a Korean Patient and Comparison with Other Asian Isolates

et al. 2020

View full text Add to dashboard Cite

show abstract

“…This close relationship with dogs, however, can pose certain risks with the potential of dogs transmitting a broad range of zoonotic pathogens, including viruses, bacteria, parasites and fungi [ 32 – 34 ]. Regarding S. stercoralis , some genotypes are dog specific while others can infect dogs and humans; hence, dogs could be reservoirs of zoonotic S. stercoralis [ 6 , 13 , 35 ]. In this review and meta-analysis, we estimated the global prevalence of S .…”

Section: Discussionmentioning

confidence: 99%

“…Many of these helminths are zoonotic with carnivores, particularly dogs and cats, responsible for transmission of nearly 43% of the zoonotic pathogens [ 1 – 4 ]. One of these zoonotic pathogens is Strongyloides stercoralis , a soil-transmitted helminth that affects 100–370 million people globally and is classified as a neglected tropical disease [ 5 , 6 ]. The main manifestations of S. stercoralis infection are gastrointestinal and cutaneous signs.…”

Section: Introductionmentioning

confidence: 99%

“…Strongyloides stercoralis also is capable of infecting canids and a range of other vertebrate hosts such as felids and non-human primates [ 6 , 13 ]. Canine S. stercoralis infection occurs most frequently in puppies and young dogs under 1 year of age and in puppies living in breeding kennels with poor sanitary conditions during hot and humid seasons [ 14 – 18 ].…”

Section: Introductionmentioning

confidence: 99%

“…Dogs and humans share certain S. stercoralis genotypes. Although there are few reports of transmission from dogs to humans, experimental infections illustrate that S. stercoralis from human origin can infect dogs, suggesting dogs can be a reservoir for human infection [ 6 , 13 , 23 , 24 ]. While there have been recent studies estimating regional and global prevalence of Strongyloides for humans and associated risk factors [ 5 , 7 , 12 , 25 ], these data are not available for infections in dogs.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Global prevalence and epidemiology of Strongyloides stercoralis in dogs: a systematic review and meta-analysis

et al. 2022

View full text Add to dashboard Cite

Background Strongyloides stercoralis, a soil-transmitted helminth, occurs in humans, non-human primates, dogs, cats and wild canids. The zoonotic potential between these hosts is not well understood with data available on prevalence primarily focused on humans. To increase knowledge on prevalence, this review and meta-analysis was performed to estimate the global status of S. stercoralis infections in dogs. Methods Following the PRISMA guidelines, online literature published prior to November 2020 was obtained from multiple databases (Science Direct, Web of Science, PubMed, Scopus and Google Scholar). Prevalence was calculated on a global and country level, by country income and climate, and in stray/animal shelter dogs versus owned dogs. Statistical analyses were conducted using R-software (version 3.6.1). Results From 9428 articles, 61 met the inclusion criteria. The estimated pooled global prevalence of S. stercoralis in dogs was 6% (95% CI 3–9%). Infection was found to be the most prevalent in low-income countries with pooled prevalence of 22% (95% CI 10–36%). The highest pooled prevalence of S. stercoralis in dogs was related to regions with average temperature of 10–20 °C (6%; 95% CI 3–11%), an annual rainfall of 1001–1500 mm (9%; 95% CI 4–15%) and humidity of 40–75% (8%; 95% CI 4–13%). Prevalence was higher in stray and shelter dogs (11%; 95% CI 1–26%) than in owned dogs (3%; 95% CI 1–7%). Conclusions As with S. stercoralis in humans, higher prevalence in dogs is found in subtropical and tropical regions and lower-income countries, locations which also can have high dog populations. While this study presents the first estimated global prevalence of S. stercoralis in dogs, it is potentially an underestimation with 15 of 61 studies relying on diagnostic methods of lower sensitivity and a paucity of data from most locations. Standardized protocols (e.g. quantity of feces and number of samples for a Baermann) in future studies could improve reliability of results. More prevalence studies and raising veterinary awareness of S. stercoralis are needed for a One Health approach to protect humans and dogs from the impact of the infection. Graphical Abstract

show abstract

Morphological and Molecular Characterisation of a New Species of Parastrongyloides (Rhabditida: Strongyloididae) from the Short-Beaked Echidna Tachyglossus aculeatus from Western Australia

et al. 2021

View full text Add to dashboard Cite

Phylogenetic relationships of Strongyloides species in carnivore hosts

Cited by 21 publications

References 31 publications

Phylogenetic Positioning of a Strongyloides stercoralis Isolate Recovered from a Korean Patient and Comparison with Other Asian Isolates

Phylogenetic Positioning of a Strongyloides stercoralis Isolate Recovered from a Korean Patient and Comparison with Other Asian Isolates

Global prevalence and epidemiology of Strongyloides stercoralis in dogs: a systematic review and meta-analysis

Morphological and Molecular Characterisation of a New Species of Parastrongyloides (Rhabditida: Strongyloididae) from the Short-Beaked Echidna Tachyglossus aculeatus from Western Australia

Contact Info

Product

Resources

About