Physical activity and cancer prevention: a systematic review of clinical trials

Abstract

Data are few, but there is some evidence to support the role of exercise in modulating various cancer pathways.

Night shift work and other determinants of estradiol, testosterone, and dehydroepiandrosterone sulfate among middle-aged nurses and midwives

“…As expected, age turned out to be the strongest determinant for each of the hormones. BMI, smoking, and recreational activity, which we tested as the potential mediators of night work showed associations with hormones in the direction reported by other researchers (49). Body weight reflects adipose tissue, which is a source of estrogens and testosterone (50).…”

Health and Economic Costs of Physical Inactivity

“…The paper also shows the strong increase of deaths due to physical inactivity compared with 2002 (5.3 million vs 1.9 million) in 2008. Moreover, physical inactivity is also a high risk factor for high blood cholesterol, overweight, obesity, atherosclerosis, musculoskeletal disorder, falls, anxiety and depression (Warburton et al, 2007;WCRF/AICR, 2007;McTiernan, 2008;Friedenreich et al, 2010a;Winzer et al, 2011;Loprinzi et al, 2012;Nunan et al, 2013).…”

Healthy aging and age-adjusted nutrition and physical fitness

“…For other kinds of cancer the evidence is still insufficient. According to a review of more than 300 publications, exercise had effects on improving several biomarkers implicated in breast and colon cancer pathways including insulin, leptin, oestrogens and apoptosis regulation [77]. In breast cancer survivors exercise affected biomarkers associated with prognosis including insulin-like growth factor axis proteins, insulin, inflammation and a large effect in enhancing immune function [77].…”