Physical activity and erectile dysfunction: meta-analysis of population-based studies

Cheng, J Y W; Ng, E M L; Ko, Jennifer S.; Chen, R Y L

doi:10.1038/sj.ijir.3901521

Cited by 89 publications

(64 citation statements)

References 19 publications

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“…The adjusted reduction of the risk of having ED was 58% for high activity and 37% for moderate activity, as compared with men with low physical activity. 32 In the Look AHEAD (Action for Health in Diabetes), 24 cardiorespiratory fitness was found to be protective of ED among the 373 diabetic men aged 45-75 years. In particular, fitness was measured by a symptom-limited graded exercise treadmill test to voluntary exhaustion; after adjustment for age and other covariates, men with greater fitness had a 39% lower risk of ED.…”

Section: Discussionmentioning

confidence: 99%

Determinants of erectile dysfunction in type 2 diabetes

et al. 2010

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This study was designed to evaluate the prevalence and correlates of ED in a population of diabetic men. Consecutive patients with type 2 diabetes were recruited among outpatients regularly attending Diabetes Clinics. Inclusion criteria for the initial selection of patients were a diagnosis of type 2 diabetes for at least 6 months but less than 10 years, age 35-70 years, body mass index (BMI) of 24 or higher, HbA1c of 6.5% or higher: a total of 555 (90.8%) of the 611 men were analyzed in this study. ED was assessed by the IIEF-5 instrument. Approximately, 6 in 10 men in our sample of diabetic men had varying degrees of erectile dysfunction: mild 9%, mild to moderate 11.2%, moderate 16.9% and severe 22.9%. The prevalence of severe ED increased with age. Higher hemoglobin A1c (HbA1c) levels were associated with ED; similarly, the presence of metabolic syndrome, hypertension, atherogenic dyslipidemia (low levels of HDL-cholesterol and high levels of triglycerides) and depression was associated with ED. Physical activity was protective of ED; men with higher levels of physical activity were 10% less likely to have ED as compared with those with the lowest level. In conclusion, among subjects with type 2 diabetes glycemic control and other metabolic covariates were associated with ED risk, whereas higher level of physical activity was protective. These results encourage the implementation of current medical guidelines that place intensive lifestyle changes as the first step of the management of type 2 diabetes.

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Section: Discussionmentioning

confidence: 99%

Determinants of erectile dysfunction in type 2 diabetes

et al. 2010

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“…The adjusted reduction of the risk of having ED was 58% for high activity and 37% for moderate activity, as compared with men with low physical activity. 69 We hypothesized that lifestyle changes aimed at reducing body weight and increasing physical activity would induce amelioration of erectile and endothelial functions in obese men. We conducted a randomized controlled trial involving 110 obese men with ED.…”

Section: Lifestyle and Sexual Functionmentioning

confidence: 99%

Obesity and sexual dysfunction, male and female

et al. 2008

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Obesity has become a worldwide public health problem of epidemic proportions, as it may decrease life expectancy by 7 years at the age of 40 years: excess bodyweight is now the sixth most important risk factor contributing to the overall burden of disease worldwide. Overweight and obesity may increase the risk of erectile dysfunction (ED) by 30-90% as compared with normal weight subjects. On the other hand, subjects with ED tend to be heavier and with a greater waist than subjects without ED, and also are more likely to be hypertensive and hypercholesterolemic. The metabolic syndrome, characterized by a clustering of risk factors associated with insulin resistance and abdominal obesity, associates with ED. Moreover, women with the metabolic syndrome have an increased prevalence of sexual dysfunctions as compared with matched control women. Lifestyle changes aimed at reducing body weight and increasing physical activity induce amelioration of both erectile and endothelial functions in obese men. Moreover, preliminary evidence suggests that a Mediterranean-style diet might be effective in ameliorating sexual function in women with the metabolic syndrome. Lifestyle changes, mainly focussing on regular physical activity and a healthy diet, are effective and safe ways to reduce cardiovascular diseases and premature mortality in all population groups; they may also prevent and treat sexual dysfunctions in both sexes.

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“…Bacon et al 20,21 showed that the level of physical activity was associated with erectile dysfunction, where men with higher physical activity are less likely to suffer from erectile dysfunction. A meta-analysis performed by Cheng et al 22 showed that moderate and intense physical activities are associated with lower risk for erectile dysfunction (OD ¼ 1 for low physical activity level, OD ¼ 0.63 for moderate level and OD ¼ 0.42 for high level). Likewise, lack of physical activity was associated with higher rates of erectile dysfunction in a Thai study.…”

Section: Discussionmentioning

confidence: 99%

Erectile dysfunction association with physical activity level and physical fitness in men aged 40–75 years

et al. 2011

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The aim of this study is to evaluate the association between physical activity level and physical fitness with erectile dysfunction in men aged 40-75 years. We examined 180 men aged 40-75 years. The individuals were evaluated for age, presence of dyslipidemia and smoking and for anthropometric parameters for the characterization of body mass index. For assessing the level of physical fitness, a test was performed to measure the indirect maximum oxygen consumption. The evaluation of erectile function was made by the International Index of Erectile Function questionnaire and assessment of physical activity level by the International Physical Activity questionnaire in its short version. This study showed that younger men with higher physical activity and better physical fitness are less likely to suffer from erectile dysfunction. Multivariable analysis through logistic regression showed that age (odds ratio (OD) ¼ 1.15; 95% confidence interval (95% CI) ¼ 1.07-1.23), physical activity (OD ¼ 10.38; 95% CI ¼ 3.94-27.39) and physical fitness (OD ¼ 4.62; 95% CI ¼ 1.75-12.25) were independent variables associated with erectile dysfunction. This study reinforces the concept that healthy habits have a direct effect on erectile function.

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Physical activity and erectile dysfunction: meta-analysis of population-based studies

Cited by 89 publications

References 19 publications

Determinants of erectile dysfunction in type 2 diabetes

Determinants of erectile dysfunction in type 2 diabetes

Obesity and sexual dysfunction, male and female

Erectile dysfunction association with physical activity level and physical fitness in men aged 40–75 years

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