Physical Activity and Health Outcomes Three Months After Completing a Physical Activity Behavior Change Intervention: Persistent and Delayed Effects

Abstract

Purpose: We previously reported the effectiveness of a 12-week physical activity behavior change intervention for breast cancer survivors postintervention with this report, aiming to determine delayed and/or persistent effects 3 months after intervention completion. Methods: Forty-one sedentary women with stage I, II, or IIIA breast cancer currently receiving hormonal therapy were randomly assigned to receive the 12-week Better Exercise Adherence after Treatment for Cancer intervention or usual care. Assessments occurred at baseline, postintervention, and 3 months postintervention.Results: Weekly minutes of greater than or equal to moderate intensity physical activity measured by accelerometer showed a significant group by time interaction (F = 3.51; P = 0.035; between group difference in the mean change from baseline to 3 months postintervention, 100.1 minute, P = 0.012). Significant group by time interactions also showed sustained improvements from baseline to 3 months postintervention in strength (F = 3.82; P = 0.027; between group difference, 11.2 kg; P = 0.026), waist-to-hip ratio (F = 3.36; P = 0.041; between group difference, À0.04; P = 0.094), and social well-being (F = 4.22; P = 0.023; between group difference, 3.9; P = 0.039). A delayed reduction in lower extremity dysfunction 3 months postintervention was noted (F = 3.24; P = 0.045; between group difference in the mean change from postintervention to 3 months followup; P = À7.6; P = 0.015). No group by time effect was noted for fitness, body mass index, percent fat, bone density, total quality of life (Functional Assessment of Cancer Therapy-General), fatigue, endocrine symptoms, cognitive function, or sleep. Conclusions: The intervention resulted in sustained improvements in physical activity, strength, central adiposity, and social well-being with lower extremity function benefits appearing 3 months after intervention completion. Testing translation in a multisite study is warranted.

A Randomized Trial of Aerobic Exercise and Sleep Quality in Lymphoma Patients Receiving Chemotherapy or No Treatments

“…No previous study has examined the effects of exercise on sleep quality in patients with lymphoma. In other cancer patient groups, results have been mixed with 3 studies showing benefit (10,14,17) and 4 studies showing no benefit (12,13,15,16).…”

“…Our subgroup analysis actually contradicts this finding, suggesting benefit only in obese patients with cancer. The null effects on sleep quality from the other 4 exercise trials consisted of 6 months of home-based combined exercise in 24 patients with multiple myeloma receiving stem cell transplant therapy (12), a home-based aerobic exercise program started either during or after treatment in 119 mixed patients with cancer (13), a partially supervised 12-week aerobic exercise program in 41 patients with breast cancer on hormone therapy (15), and a 4 week home-based walking and strength training program in 38 patients with breast or prostate cancer receiving radiation therapy (16). These mixed results from exercise and sleep quality trials in patients with cancer could be attributable to numerous factors including patient characteristics, treatment status, and the exercise prescription.…”

“…Seven randomized controlled trials (RCT) have examined the effects of exercise on sleep quality in patients with cancer (10,(12)(13)(14)(15); however, these trials have largely been pilot studies limited by small sample sizes under 75 (10,12,(14)(15)(16)(17), heterogeneous samples with mixed cancer diagnoses (9,12,15), unsupervised exercise interventions (10, 12-14, 16, 17), and short exercise interventions of <12 weeks (10,16,17). Three of these trials have shown significant improvements in sleep quality (10,14,17) whereas 4 have not (12,13,15,16).…”

Wearable Sensor/Device (Fitbit One) and SMS Text-Messaging Prompts to Increase Physical Activity in Overweight and Obese Adults: A Randomized Controlled Trial

“…From the literature [52][53][54][55] we assumed that the combined intervention effect on the standardized mean difference in steps would be at least 17% higher at follow-up than for the Fitbit only group. We assessed power at 80% with an alpha level of 0.05 for a two-sided two-sample t test.…”

Does Switching from Tamoxifen to an Aromatase Inhibitor Result in Weight Change in Postmenopausal Breast Cancer Patients?~!2010-04-23~!2010-07-08~!2010-07-26~!

“…Caloric intake and energy expenditure were assumed to be relatively constant over the two year period of the study for each patient. Recent efforts at determining the impact of aerobic exercise interventions in breast cancer survivors have not yielded changes in BMI or weight [23][24][25] despite sustained changes in exercise patterns and body composition.…”