Physical activity and health outcomes in persons with haemophilia B

Niu, Xiaoli; Poon, Jiat Ling; Riske, Brenda; Zhou, Zheng–Yi; Ullman, Megan M.; Lou, Mimi; Baker, Jean H.; Koerper, Marion A.; Curtis, Randall; Nichol, Michael B.

doi:10.1111/hae.12485

Cited by 26 publications

(68 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The oldest age group in our study (55–88 years) experienced an improvement in joint mobility and physical function from 2001 to 2012. However, this group may encounter new clinical challenges due to age-related comorbidities [24], e.g., obesity [25]. We did not include questions on height and weight, which should be included in future research.…”

Section: Discussionmentioning

confidence: 99%

Joint Mobility and Physical Function of Danish Hemophilia Patients: A Three-Wave Panel Study Spanning 24 Years

et al. 2018

View full text Add to dashboard Cite

Background: The positive effects of factor treatment of hemophilia are well established, but the long-term outcomes are not well documented. This panel study evaluated changes in bleeding frequency, joint mobility, physical function, and symptoms in Danish patients with moderate to severe hemophilia A or B over 24 years. Methods: Three anonymous surveys were conducted in 1988, 2001, and 2012 targeting Danish patients with moderate to severe hemophilia, and the study participants, respectively, were 128, 156, and 164 male patients with hemophilia (PWH). The number of bleeding episodes, the use of factor concentrate, comorbidities, joint mobility, physical function, and symptoms were evaluated by means of self-reporting. Trends over time were analyzed using ordinal and multinomial logistic-regression models controlling for age group. Results: The proportion of PWH in the oldest age group (55–88 years) increased from 4% in 1988 to 18% in 2012. In 1988, a high risk of bleeding episodes was primarily found in the age group of 16–34 years. In 2012, a high risk was primarily found in the age group of 35–54 years. Joint mobility and physical function increased significantly from 1988 to 2012 but showed a noticeable decrement in the older age groups, even in 2012. Pain in the extremities, anxiety, and depression decreased significantly, but back pain increased. No significant changes were found for 7 other symptoms. Conclusions: Significant improvements in joint mobility and physical function have occurred over the last 24 years, but PWH > 35 years still experience a decline in these areas with age. This decline underscores the importance of life-long treatment and continuous rehabilitation of PWH.

show abstract

Section: Discussionmentioning

confidence: 99%

Joint Mobility and Physical Function of Danish Hemophilia Patients: A Three-Wave Panel Study Spanning 24 Years

et al. 2018

View full text Add to dashboard Cite

show abstract

“…26 The Arabic version of the questionnaire that has been validated with acceptable reliability and validity was used. 26 The Arabic version of the questionnaire that has been validated with acceptable reliability and validity was used.…”

Section: International Physical Activity Questionnaire (Ipaq)mentioning

confidence: 99%

“…26 Scores were calculated by averaging the PA undertaken in the previous week and the PA undertaken in a typical week. 26 Scores were calculated by averaging the PA undertaken in the previous week and the PA undertaken in a typical week.…”

Section: Children's Physical Activity Questionnaire (Cpaq)mentioning

confidence: 99%

Nutritional status of children and adolescents with haemophilia in Basra, Iraq

Abdulaziz¹,

Hassan²

2019

Haemophilia

View full text Add to dashboard Cite

Introduction Patients with haemophilia are at increased risk of being overweight or obese, which in turn may have a profound effect on morbidity and quality of life. Aims To assess the nutritional status of paediatric patients with haemophilia and identify possible risk factors that may adversely affect their nutritional status. Methods A case‐control study was performed on 63 haemophilia patients and 135 control subjects aged 5‐18 years. For all participants, weight, height and body mass index Z (BMIZ) score were assessed. Physical activity (PA) was assessed using the International Physical Activity Questionnaire and the Children's Physical Activity Questionnaire for participants ≥15 years and 5‐14 years old, respectively. Results The frequency of overweight and obesity was 36.29% among the control group compared with 23.81% among patients, while thinness was higher in patients with haemophilia (19.05%) compared with 9.63% in the control group, P = .042. Low PA was reported in 22.73% of haemophilia patients aged 5‐14 years compared with 2.06% in the control group, P < .001. However, no difference in PA was reported among participants aged ≥15 years. There were no significant differences in the frequency of nutritional problems among patients with respect to age, type of haemophilia, disease severity and hepatitis C seropositivity. Regression analysis revealed a negative association between paternal educational level and high BMIZ in patients ≥15 years, P = .028. Conclusions Paediatric patients seem to have lower BMIZ than the control group. In addition, most of the studied factors were not found to predict either high or low BMIZ among studied patients.

show abstract

“…Over the past years also sport therapeutic treatment options have become a major focus in the treatment of PwH, and their positive effects on health have been described in various studies including pain, range of motion and strength . Niu et al showed that physically active PwH had a better state of health. With regard to HRQoL and self‐confidence, von Mackensen revealed a positive effect of sports therapy .…”

Section: Introductionmentioning

confidence: 99%