Physical Activity Combined with Massage Improves Bone Mineralization in Premature Infants: A Randomized Trial

Aly, Hany; Moustafa, M. M.; Hassanein, Sahar M A; Massaro, An N.; Amer, Hanna A; Patel, Kantilal M.

doi:10.1038/sj.jp.7211083

Cited by 56 publications

(62 citation statements)

References 24 publications

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“…However, some studies have demonstrated that passive exercise for 5 min per day in the first weeks of life promotes greater bone mineralization, Physical therapy for bone mineralization in premature infants CM Vignochi et al using other evaluation methods. [17][18][19][20][21][23][24][25] This study clearly demonstrated that specific motor physical therapy applied 5 times per week for 15 min, over a period of 4 weeks, produced a significant improvement in weight gain, body length, BMC, BMD, LM and BA values measured by total body DEXA when compared to the CG, which did not receive motor physical therapy. Multiple factors influence bone growth and development.…”

Section: Discussionsupporting

confidence: 51%

“…[10][11][12][13][14][15][16][17] Some researchers have recently suggested that 5 min per day, 5 times per week for 4 weeks of passive exercises with soft compressions result in increased bone mineral density (BMD) in very low birth weight premature infants. [18][19][20][21] This prospective randomized controlled clinical assay was carried out with the objective of evaluating the effects of a motor physical therapy protocol, 15 min per day, 5 days per week, on bone mineralization in very low birth weight preterm infants.…”

Section: Introductionmentioning

confidence: 99%

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Effects of motor physical therapy on bone mineralization in premature infants: a randomized controlled study

2008

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Objective: To study the effect of physical therapy on bone mineralization, weight gain and growth in preterm infants.Method: After fulfilling the inclusion criteria, preterm infants were matched for gestational age and birth weight and then randomly assigned to the physiotherapy group (PG, n ¼ 15) and control group (CG, n ¼ 14). The PG received motor physical therapy for 15 min daily, 5 times per week until hospital discharge. Bone mineralization was measured by total body dual energy X-ray beam absorptiometry (DEXA) at the onset and end of the study. Statistical analysis was realized by ANCOVA and linear correlation tests. Result:The physical therapy group (PG) presented greater body weight gain per day (27.4 ± 2.4 vs 21.01 ± 4.4 g, P<0.001) and length (1.3 ± 0.3 vs 0.8 ± 0.2 cm week À1 , P<0.001) than did the control group (CG). Body composition values verified by DEXA were greater for the PG. The mean gain in bone mineral content (BMC) (mg) was greater in the PG (434±247.5 vs À8.9±11.4, P<0.001), as was the mean bone mineral density (BMD) gain (mg cm À2 ) (8.4 ± 5.6 vs À3.1 ± 5.5, P<0.001). The gain in bone area (BA,cm 2 ) was 10.3±5 in the PG vs 1.5 ± 2 in the CG (P<0.001). The gain in lean mass (LM) (g) in the PG was also greater than in the CG (271.1±21.4 vs 109.1±1.0, P<0.009). The fat mass (g) was similar between the groups (P ¼ 0.432). Conclusion:These results showed that physiotherapy in preterm infants produced greater gains in growth, body weight, BMC, BMD, BA and LM.

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Section: Discussionsupporting

confidence: 51%

Section: Introductionmentioning

confidence: 99%

Effects of motor physical therapy on bone mineralization in premature infants: a randomized controlled study

2008

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“…19 Improved bone mineralization and skeletal growth have been associated with programs of daily physical activity in preterm infants. 8,[20][21][22][23] Thus physical activity may improve weight gain through a variety of mechanisms affecting body mass of all typesFadipose, muscle and bone. Additional mechanisms have been proposed that provide a basis for the benefits of massage alone in the promotion of growth.…”

Section: Discussionmentioning

confidence: 99%

“…Preliminary studies have suggested that massage therapy with KS may have positive effects on preterm infants including greater weight gain, [1][2][3][4][5][6][7] improved bone mineralization, 8 earlier hospital discharge, [1][2][3] and more optimal behavioral and motor responses 2-4,9,10 compared to controls. However, there is inconsistency of these findings across studies and methodological concerns with previous trials have led some authors to caution widespread and routine use of preterm infant massage.…”

Section: Introductionmentioning

confidence: 99%

Massage with kinesthetic stimulation improves weight gain in preterm infants

et al. 2009

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Objective: The aim of this study was to evaluate the effects of massage with or without kinesthetic stimulation on weight gain and length of hospital stay in the preterm infant.Study Design: A prospective randomized clinical trial was conducted evaluating the effects of massage with or without kinesthetic stimulation (KS) on weight gain and length of stay (LOS) in medically stable premature (<1500 g and/or p32 weeks gestational age) neonates. Infants were randomized either to receive no intervention (control), massage therapy alone (massage), or massage therapy with KS (M/KS). Linear regression analysis was performed to evaluate differences in the primary outcomes between the groups after controlling for covariates. Post hoc analysis with stratification by birthweight (BW> and <1000 g) was also performed.Result: A total of 60 premature infants were recruited for this study; 20 infants in each group. Average daily weight gain and LOS were similar between the groups after controlling for covariates. For infants with BW>1000 g, average daily weight gain was increased in the intervention groups compared to control. This effect was mainly attributable to the M/KS group. Conclusion:Massage with KS is a relatively simple and inexpensive intervention that can improve weight gain in selected preterm infants. Length of hospital stay is not impacted by massage with or without KS. Further studies are needed to evaluate the effect of massage in the extremely low BW(<1000 g) infant.

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“…202 Massage has been associated with a shift from less total sleep, towards more periods of drowsiness 188 and post-massage sleep may be increased. 193 The use of gentle touch has been associated with lower levels of AS, motor activity and behavioral distress, but no differences were seen in weight gain or behavioral organization.…”

Section: Role Of Sleep In Brain Developmentmentioning

confidence: 99%

The development of potentially better practices to support the neurodevelopment of infants in the NICU

et al. 2007

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Objective: To review the existing evidence used to identify potentially better care practices that support newborn brain development.Study Design: Literature review.Result: Sixteen potentially better practices are identified and grouped into two operational clinical bundles based upon timing for recommended implementation. Conclusion:Existing evidence supports the implementation of selected care practices that potentially may support newborn brain development.

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Physical Activity Combined with Massage Improves Bone Mineralization in Premature Infants: A Randomized Trial

Abstract: A combined massage and physical activity protocol improved bone formation (PICP) but did not affect bone resorption (Pyd). Pyd increased over time in both groups, possibly due to continuous bone resorption and Ca mobilization.

Cited by 56 publications

References 24 publications

Effects of motor physical therapy on bone mineralization in premature infants: a randomized controlled study

Effects of motor physical therapy on bone mineralization in premature infants: a randomized controlled study

Massage with kinesthetic stimulation improves weight gain in preterm infants

The development of potentially better practices to support the neurodevelopment of infants in the NICU

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