Physical Activity Is Associated With Better Vascular Function in Children and Adolescents With Congenital Heart Disease

Lopez, Jimmy; Voss, Christine; Kuan, Mimi; Hemphill, Nicole M.; Sandor, George G.S.; Harris, Kevin C.

doi:10.1016/j.cjca.2019.12.019

Cited by 20 publications

(8 citation statements)

References 46 publications

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“…9,10 This was unsurprising given that only one-third of Canadian children, and only 25% of those with CHD, meet the guidelines. 11,12 Therefore, reduced physical activity due to COVID-19 may not have severe long-term health impacts if the implemented measures to prevent a catastrophic pandemic are reasonably brief. However, it will be important to understand and model the long-term impact of significantly reduced physical activity on health for these patients should the present approach need to be maintained for months, as indicated by Prime Minister Trudeau on April 8, 2020.…”

Section: Discussionmentioning

confidence: 99%

Reduced Physical Activity During COVID-19 Pandemic in Children With Congenital Heart Disease

Hemphill

Kuan

Harris

2020

Canadian Journal of Cardiology

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105

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Children with congenital heart disease (CHD) are at risk for both COVID-19 and secondary cardiovascular outcomes. Their increased cardiovascular risk may be mitigated through physical activity, but public health measures implemented for COVID-19 can make physical activity challenging. We objectively measured the impact of the COVID-19 pandemic on physical activity, continuously measured by Fitbit step counts, in children with CHD.Step counts were markedly lower in late March and early April 2020, compared with 2019 and early March 2020. It is vital to understand how precautions for COVID-19 will affect the health of children with CHD, especially if they persist long term. MethodsData were collected as part of an ongoing prospective cohort study in children with moderate to severe CHD. The

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Section: Discussionmentioning

confidence: 99%

Reduced Physical Activity During COVID-19 Pandemic in Children With Congenital Heart Disease

Hemphill

Kuan

Harris

2020

Canadian Journal of Cardiology

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105

100

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“…One study reported of increased arterial stiffness in low-active children with CHD compared to high-active children with CHD and healthy controls [20]. Another study reported of an inverse association between high levels of MVPA and lower aortic PWV in children with CHD [21]. This association is particularly important in the way of preventing cardiovascular disease in this patient cohort who showed reduced elasticity of the vascular system already in childhood [6,7].…”

Section: Introductionmentioning

confidence: 80%

“…Lopez and colleagues [21] reported of an inverse association between MVPA and aortic PWV after adjusting for sex, age and BMI in 104 children with CHD at a mean age of 12 years. In contrast to our study their patient cohort was rather inactive with an average of 46.7 ± 20.0 min MVPA per day and only 25% of the cohort meeting the WHO recommendation, which markedly differs from the 80% in our patient cohort [21].…”

Section: Discussionmentioning

confidence: 99%

Association between Objectively Measured Physical Activity and Arterial Stiffness in Children with Congenital Heart Disease

Willinger

Brudy

Oberhoffer‐Fritz

et al. 2021

JCM

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Background: The association between physical activity (PA) and arterial stiffness is particularly important in children with congenital heart disease (CHD) who are at risk for arterial stiffening. The aim of this study was to examine the association between objectively measured PA and arterial stiffness in children and adolescents with CHD. Methods: In 387 children and adolescents with various CHD (12.2 ± 3.3 years; 162 girls) moderate-to-vigorous PA (MVPA) was assessed with the “Garmin vivofit jr.” for 7 consecutive days. Arterial stiffness parameters including pulse wave velocity (PWV) and central systolic blood pressure (cSBP) were non-invasively assessed by oscillometric measurement via Mobil-O-Graph®. Results: MVPA was not associated with PWV (ß = −0.025, p = 0.446) and cSBP (ß = −0.020, p = 0.552) in children with CHD after adjusting for age, sex, BMI z-score, peripheral systolic blood pressure, heart rate and hypertensive agents. Children with CHD were remarkably active with 80% of the study population reaching the WHO recommendation of average 60 min of MVPA per day. Arterial stiffness did not differ between low-active and high-active CHD group after adjusting for age, sex, BMI z-score, peripheral systolic blood pressure, heart rate and hypertensive agents (PWV: F = 0.530, p = 0.467; cSBP: F = 0.843, p = 0.359). Conclusion: In this active cohort, no association between PA and arterial stiffness was found. Longer exposure to the respective risk factors of physical inactivity might be necessary to determine an impact of PA on the vascular system.

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“…Organization cut-offs. As part of a cohort study, clinical characteristics of this cohort have been described in detail [15].…”

Section: Competing Interestsmentioning

confidence: 99%

Children with congenital heart disease exhibit seasonal variation in physical activity

et al. 2020

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Objective We sought to identify seasonal variation in physical activity that different physical activity measurement tools can capture in children with congenital heart disease. Methods Data were collected as part of a prospective cohort study at BC Children’s Hospital, Vancouver, Canada. Daily step counts of children aged 9–16 years with moderate-to-severe CHD were assessed continuously for 1-year via a commercial activity tracker (Fitbit Charge 2™). Physical activity levels were also assessed conventionally at one time-point via accelerometers (ActiGraph) and physical activity questionnaires. Results 156 children (mean age 12.7±2.4 years; 42% female) participated in the study. Fitbit data (n = 96) over a 1-year period clearly illustrated seasonal peaks (late spring and autumn) and dips (winter and summer school holidays) in physical activity levels, with group mean values being below 12,000 steps per day throughout the year. According to conventional accelerometry data (n = 142), 26% met guidelines, which tended to differ according to season of measurement (spring: 39%, summer: 11%, fall: 20%, winter: 39%; p-value = 0.053). Questionnaire data (n = 134) identified that the most widely reported activities were walking (81%) and running (78%) with walking being the highest in summer and fall and running in winter and spring. Furthermore, regardless of overall activity levels the children exhibit similar seasonal variation. Conclusions We demonstrated that physical activity level changes across seasons in children with CHD. It is important to be aware of these fluctuations when assessing and interpreting physical activity levels. Season specific counselling for physical activity may be beneficial in a clinical setting.

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Physical Activity Is Associated With Better Vascular Function in Children and Adolescents With Congenital Heart Disease

Cited by 20 publications

References 46 publications

Reduced Physical Activity During COVID-19 Pandemic in Children With Congenital Heart Disease

Reduced Physical Activity During COVID-19 Pandemic in Children With Congenital Heart Disease

Association between Objectively Measured Physical Activity and Arterial Stiffness in Children with Congenital Heart Disease

Children with congenital heart disease exhibit seasonal variation in physical activity

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