Physical Activity, Physical Fitness and Risk of Myocardial Infarction1

Wilhelmsen, Lars; Tibblin, Gösta; Aurell, Mattias; Bjure, J.; Ekström-Jodal, B; Grimby, Gunnar

doi:10.1159/000399526

Cited by 114 publications

(75 citation statements)

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“…In a cohort study of Caucasians, there was a positive association between physical activity level and MET [29]. In other validation studies, physical activity measured using this question correlated with the IPAQ-L (an international questionnaire about physical activity) [26] and aerobic capacity [27,28].…”

Section: Study Design and Populationmentioning

confidence: 81%

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Leisure time physical activity and risk of non-vertebral fracture in men and women aged 55 years and older: the Tromsø Study

et al. 2012

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Although the positive association between physical activity and bone mineral density (BMD) is well established, few epidemiological studies have investigated the long-term associations between physical activity during adulthood and BMD later in life. The aim of this prospective, population-based study was to examine the association between leisure time physical activity in adulthood and areal BMD (aBMD) later in life. We examined 1,766 women and 1,451 men aged 20-54 years at baseline who were followed up 22 years later, as part of a population-based study in Norway. Leisure time physical activity was assessed by questionnaire at baseline and followup. aBMD was measured at the hip and forearm at follow-up, using X-ray absorptiometry. The association between aBMD and physical activity was analyzed using general linear models. We observed a positive linear trend in aBMD across physical activity levels in both women and men, after adjustments for baseline age, height, weight, and smoking status (P < 0.05). The relationship between aBMD and leisure time physical activity was consistent over different sites of the hip (total hip, femoral neck and trochanter area) and forearm (distal and ultradistal area).In a subsample of 2436 men and women under 70 years of age, those who where sedentary at both baseline and follow-up (6%) had lower aBMD than those who were moderately active or active at both baseline and follow-up (71%) (P ≤ 0.01). This study suggests that leisure time physical activity in adulthood is associated with higher aBMD and reduced risk of osteoporosis later in life.

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Section: Study Design and Populationmentioning

confidence: 81%

“…In the present study, we included participants from the Leisure time physical activity assessed according to this question has been validated against various measures [26][27][28][29]. In a cohort study of Caucasians, there was a positive association between physical activity level and MET [29].…”

Section: Study Design and Populationmentioning

confidence: 99%

Leisure time physical activity and risk of non-vertebral fracture in men and women aged 55 years and older: the Tromsø Study

et al. 2012

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“…First, physical exercise during leisure time and work time was investigated with a self-rating questionnaire, which classified activity into a four-grade scale during winter and summer time (20). Secondly, participants were interviewed by a dietician to describe their usual activity pattern during an ordinary 'day' and daily activities were assessed in periods of 15-min intervals as either 'active' (standing, walking, housework, and sports) or 'inactive' (sleeping, lying down, reading, sitting, and watching television).…”

Section: Assessments Of Physical Activitymentioning

confidence: 99%

Hypothalamic involvement and insufficient sex steroid supplementation are associated with low bone mineral density in women with childhood onset craniopharyngioma

Holmer

Popović²,

Ekman³

et al. 2011

European Journal of Endocrinology

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Context: Data on bone mineral density (BMD) are lacking in adults with childhood onset (CO)-craniopharyngioma (CP) with hypothalamic damage from the tumor. In patients with CO GH deficiency, BMD increases during GH treatment. Objective: The aims were to evaluate BMD in adults with CO-CPs on complete hormone replacement, including long-term GH and to evaluate the impact of hypothalamic damage on these measures. Design and participants: BMD (dual-energy X-ray absorptiometry), markers of bone turn over, physical activity and calcium intake were assessed in 39 CO-CP adults (20 women), with a median age of 28 (17-57) years, in comparison with matched population controls. Results: Late puberty induction was recorded in both genders, but reduced androgen levels in females only. Only CP women had lower BMD (PZ0.03) at L2-L4, and reduced Z-scores at femoral neck (PZ0.004) and L2-L4 (PZ0.004). Both genders had increased serum leptin levels (PZ0.001), which significantly correlated negatively with BMD at L2-L4 (PZ0.003; rZK0.5) and 45% of CP women had Z-score levels %K2.0 S.D. Furthermore, 75% of those with a Z-score %K2.0 S.D. had hypothalamic involvement by the tumor. Calcium intake (PZ0.008) and physical activity (PZ0.007) levels were reduced in CP men only. Levels of ostecalcin and crossLaps were increased in CP men only. Conclusions: Despite continuous GH therapy, low BMD was recorded in CO-CP females. Insufficient estrogen and androgen supplementation during adolescence was the main cause, but hypothalamic involvement with consequent leptin resistance was also strongly associated with low BMD in both genders.

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“…This highlights the need for brief instruments for measuring health related behaviours such as physical activity (PA) in large epidemiological studies. A short instrument developed in Gothenburg, Sweden in the 1960s to measure leisure-time PA (LPA) [2,3] has for decades been used in Norwegian health surveys. This instrument is here referred to as the Gothenburg instrument.…”

Section: Introductionmentioning

confidence: 99%

“…Before being widely used, the Gothenburg instrument was validated by interview and compared with maximal oxygen uptake (VO 2max ) and working capacity in men [2,3].…”

Section: Introductionmentioning

confidence: 99%

Two short questionnaires on leisure-time physical activity compared with serum lipids, anthropometric measurements and aerobic power in a suburban population from Oslo, Norway

et al. 2007

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Physical Activity, Physical Fitness and Risk of Myocardial Infarction1

Cited by 114 publications

References 0 publications

Leisure time physical activity and risk of non-vertebral fracture in men and women aged 55 years and older: the Tromsø Study

Leisure time physical activity and risk of non-vertebral fracture in men and women aged 55 years and older: the Tromsø Study

Hypothalamic involvement and insufficient sex steroid supplementation are associated with low bone mineral density in women with childhood onset craniopharyngioma

Two short questionnaires on leisure-time physical activity compared with serum lipids, anthropometric measurements and aerobic power in a suburban population from Oslo, Norway

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