“…conventional spectroscopies, do not typically reach the spatial resolution needed for single nano-fiber detection and could only look at composites as quasi-homogeneous materials. 7,8 In the present study, we propose the use of nano-resolved IR microscopy, namely infrared scattering-type scanning near field optical microscopy (IR s-SNOM), supported by micro Attenuated Total Reflection (ATR) Fourier Transform Infrared (FTIR) imaging, to address the study of a binary fibrous material named Silkothane®. 9 In Silkothane® the combination of natural silk fibroin (SF) and synthetic medical grade polyurethane (PU) proved to be highly suitable for TE applications.…”