Physical basis of emission, ejaculation, and orgasm in the male

Newman, Harry; Reiss, H. E.; Northup, Jane D.

doi:10.1016/0090-4295(82)90186-8

Cited by 111 publications

(51 citation statements)

References 56 publications

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“…(Rose, 1953;Kedia & Markland, 1976). During this process external and internal sphincter synchrony along with proper peristaltic flow is required to encourage semen in an antegrade direction (Schienen & Hupe, 1976;Newman et al, 1982;Thomas, 1983) as demonstrated by radiological studies of rams (Hovell et al, 1969) and marsupials (Rodger & Polliti, 1981). The lack of synchronous flow therefore traps semen in the posterior urethra and allows it to flow back into the bladder when stimulation ceases.…”

Section: Resultsmentioning

confidence: 99%

Viable spermatozoa in the bladder after electroejaculation of lion-tailed macaques (Macaca silenus)

et al. 1989

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Summary. The bladder of 6 lion-tailed macaques was emptied and flushed with sterile saline. TALP-Hepes buffer was infused and the animals were electroejaculated. After electroejaculation, the semen quality was determined in the ejaculate and the bladder infusate. Of the 15 ejaculates analysed, a mean (\m=+-\s.e.m.) sperm count of 133\m=.\8(\m=+-\30\m=.\7) \m=x\106 with 69\m=.\5( \ m=+-\ 6\m=.\0%motility was obtained in the infusate as compared to the sperm count of 72\m=.\4 (\ m=+-\38\m=.\6 \m=x\106 with significantly lower (47\m=.\7\ m=+-\5\m=.\8%motility in the ejaculate.

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Section: Resultsmentioning

confidence: 99%

Viable spermatozoa in the bladder after electroejaculation of lion-tailed macaques (Macaca silenus)

et al. 1989

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“…Sexual spinal reflexes, including erection and ejaculation, are under tonic inhibition in all mammals (Newman et al, 1982;DeGroat and Steers, 1988;Marson and McKenna, 1990;Sachs and Britan, 1990). Studies in the male rat using electrolytic lesions suggest that the nPGi is the source of this tonic descending inhibition.…”

Section: Functional Implications Of a Steroidresponsive Mpo3 Pag3npgimentioning

confidence: 96%

Distribution of gonadal steroid receptor–containing neurons in the preoptic–periaqueductal gray–brainstem pathway: A potential circuit for the initiation of male sexual behavior

Murphy

Hoffman

2001

J of Comparative Neurology

122

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The present study used anterograde and retrograde tract tracing techniques to examine the organization of the medial preoptic-periaqueductal gray-nucleus paragigantocellularis pathway in the male rat. The location of neurons containing estrogen (alpha subtype; ER alpha) and androgen receptors (AR) were also examined. We report here that injection of the anterograde tracer biotinylated dextran amine (BDA) into the medial preoptic (MPO) produced dense labeling within the periaqueductal gray (PAG); anterogradely labeled fibers terminated in close juxtaposition to neurons retrogradely labeled from the nucleus paragigantocellularis (nPGi). Dual immunostaining for Fluoro-Gold (FG) and ER alpha or FG and AR showed that over one-third of MPO efferents to the PAG contain receptors for either estrogen or androgen. In addition, approximately 50% of PAG neurons retrogradely labeled from the nPGi were immunoreactive for either ER alpha or AR. These results are the first to establish an MPO-->PAG-->nPGi circuit and further indicate that gonadal steroids can influence neuronal synaptic activity within these sites. We reported previously that nPGi reticulospinal neurons terminate preferentially within the motoneuronal pools of the lumbosacral spinal cord that innervate the pelvic viscera. Together, we propose that the MPO-->PAG-->nPGi circuit forms the final common pathway whereby MPO neural output results in the initiation and maintenance of male copulatory reflexes.

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“…With increasing pressure, a sense of inevitability develops [22]. Cerebral control of ejaculation is minimal at this point [25].…”

Section: Physiology Of Emission and Ejaculationmentioning

confidence: 99%

Ejaculatory failure

Witt

Grantmyre²

1993

World J Urol

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Although anejaculation is a relatively uncommon occurrence in the general population, over 12,000 new cases are reported annually. Anejaculation may result from spinal cord injury (SCI), retroperitoneal lymph node dissection (RPLND), diabetes mellitis, transverse myelitis, multiple sclerosis, or psychogenic disorders. At least 30% of men with this problem are or will be married and many will seek help to remedy their infertile state. The evolution of technique and instrumentation over the least 30 years has made electroejaculation an accessible and acceptable form of therapy. Recent successes in inducing ejaculation by means of rectal probe electrostimulation or vibratory stimulation combined with assisted reproductive techniques, such as zygote intrafallopian transfer (ZIFT), gamete intrafallopian transfer (GIFT), and in vitro fertilization (IVF), have provided these men a means of producing their own biologic offspring.

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Physical basis of emission, ejaculation, and orgasm in the male

Cited by 111 publications

References 56 publications

Viable spermatozoa in the bladder after electroejaculation of lion-tailed macaques (Macaca silenus)

Viable spermatozoa in the bladder after electroejaculation of lion-tailed macaques (Macaca silenus)

Distribution of gonadal steroid receptor–containing neurons in the preoptic–periaqueductal gray–brainstem pathway: A potential circuit for the initiation of male sexual behavior

Ejaculatory failure

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