2023
DOI: 10.17816/rcf567782
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Physical-chemical repurposing of drugs. History of its formation in Russia

Aleksandr L. Urakov,
Petr D. Shabanov

Abstract: It is reported that the traditional scheme of finding and developing a new drug and conducting the whole complex of preclinical studies requires several thousand chemical compounds, hundreds of millions of US dollars and more than 12 years of work. It is shown that physicochemical pharmacology was born in Russia at the end of the 20th century, which in our days has been transformed into physicochemical repurposing of known medicines. The first successfully repurposed known drug was a solution of 4% potassium c… Show more

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