Adversities facing people with disabilities include barriers to meeting daily needs and to social life. Yet, too, fundamental social devaluation erodes an individual's capacity to retain title to the cultural category of a full person. These cultural adversities are important components in the disablement process. The cultural meanings for physical dependency convey images of childlike, dependent, incomplete persons near death. Using interviews with middle aged and elderly polio survivors, the author identifies key cultural categories, the expectations and values linked with disability and describe the strategies people use to confront, or not, the erosion of personhood. The importance of understanding the category of the person, its historical setting, and evolution are highlighted. Finally, the inversion of traditional cultural logics for defining the personhood of individuals with disabilities is illustrated.Severe physical impairments pose a host of hardships, some of which are more obvious than others. Impairments limit the ability to do basic daily tasks that sustain the body and the spirit. Eating, moving around, bathing, and taking part in valued personal and social life through holding a job and leisure activities all require extra efforts. Being unable to perform valued activities fosters social devaluation and low self-regard. Yet, the social devaluation is corrosive to people with disabilities at a more implicit cultural level.One of the cultural consequences of having disabilities is that an individual's identity as a complete person comes into question rather than remaining taken for granted. Being unable to fully perform normatively valued activities and roles in the workplace, home, and community challenges an individual's core identity as a full adult person. The erosion of personhood that is associated with disability is a cultural level adversity that is not well understood. The aim of this article is to examine and illustrate these issues. It will contribute an understanding of individual values, motivations, and actions as situated within an ecology of cultural contexts one of which is the category of personhood. To begin, basic concepts and orientations need to be made explicit.