Physical Exercise is More Effective than HRT in Improving Lipid Profile Status in Postmenopausal Women

Abstract

Disturbances of lipid profile in postmenopausal women may occur due to hormonal changes and physical inactivity which ultimately increases the risk of atherosclerosis, CHD and MI. Physical exercise may play a significant role in the management of dyslipidemia among postmenopausal women than HRT The study was carried out to compare and contrast between the effects of physical exercise and HRT in improving lipid profile status among postmenopausal women. This study was carried out in the Department of Physiology, Sir Salimullah Medical College, Dhaka, from 1st January, 2009 to 31st December, 2009. A total number of 90 postmenopausal women having age ranged from 50-60 years were included in the study. Among 90 postmenopausal women, 30 were performing regular physical exercise, 30 were receiving HRT and 30 were sedentary postmenopausal women without receiving HRT. Lipid profile such as TC, HDL-C, LDL-C, TG and fasting blood sugar of all the participants were estimated in Physiology laboratory, SSMC Mitford, Dhaka. The statistical analysis was done by using appropriate test as applicable. Mean serum TC, LDL-C and TG were significantly (p<0.001) higher and mean HDL-C was significantly (p<0.001) lower in sedentary postmenopausal women than those of postmenopausal women with regular physical exercise and postmenopausal women receiving HRT. Again, TC, LDL-C and TG were comparative higher in postmenopausal women receiving HRT than those of postmenopausal women with regular physical exercise and HDL-C were almost similar among these two groups of women. Conclusion: Physical exercise could be more effective than HRT in improving lipid profile status in postmenopausal women. DOI: http://dx.doi.org/10.3329/bjpp.v27i1-2.20068 Bangladesh J Physiol Pharmacol 2011; 27(1&2):9-12

Lipid profile, cardiorespiratory function and quality of life of postmenopausal women improves with aerobic exercise

“…This concurs with study that reported non-significant improvement in HDL-C and LDL-C of obese postmenopausal women (Trabka et al, 2014). Significant increase in HDL-C and significant decrease in LDL-C were however reported in overweight hypertensive Egyptian postmenopausal women on medication (Ammar, 2015) and in a cross-sectional study of postmenopausal women exercising and receiving HT separately (Ferdous et al, 2011). The non-significant decrease in TC by 2.7L% observed in this study contrasts the significant increase in TC observed in an aerobic exercise training group of elderly postmenopausal women (Fahlman, Boardley, Lambert, & Flynn, 2002 Total cholesterol to HDL ratio (cardiovascular risk ratio) has a greater predictive capacity than the isolated components of lipid profile which could be a sensitive and specific index of cardiovascular risk.…”