“…Depression is associated with asthma, back problems, gastrointestinal disorders, genitourinary conditions, musculoskeletal conditions, fibromyalgia, immunodeficiency syndrome, cancer, cardiac diseases, and endocrine disorders (Gagnon and Patten, 2002; Wittchen, Lieb, Wunderlich, and Schuster, 1999). Substance dependence is associated with cardiovascular, neurological, gastrointestinal, respiratory, dermatological, and dental problems (Keaney et al, 2011). Clinical trials however, often exclude participants with severe medical illnesses (Zimmerman, Mattia, and Posternak, 2002) or do not assess physical health problems (e.g., Bockting et al, 2005; Liu et al, 2009).…”