Physical Inactivity, Water Intake and Constipation as Risk Factors for Colorectal Cancer among Adults in Jordan

Abstract

Background: Physical activity has been found to play a role in cancer prevention. The purpose of this matched case-control study was to investigate the association between physical activity levels, water intake, constipation and colorectal cancer (CRC). Materials and Methods: Two hundred and thirty-two patients diagnosed with CRC (125 male, 107 female) were enrolled in this case-control study. Cases were matched to 271 population controls (137 male, 134 female). Results: Drinking more than 4 cups of water daily decreased the risk of CRC by 33-42%; however, this effect was non-significant. Having constipation was found to be a significant risk factor for developing CRC with an OR=6.284 (95%CI=2.741-14.40). With reference to sedentary behavior, minimum activity (600-3000 Metabolic Equivalents Task (MET)) had 43% protection against CRC and the level of Health Enhancing Physical Activity OR was 0.58 (at 95%CI; 0.37-0.92). A significant negative association was found between CRC and physical activity levels expressed as both METs and MET-hours/week (p for trend=0.017 and 0.03, respectively). Among females, a significant trend of reduction in CRC by 62% was observed with increasing the level of physical activity expressed in MET (p for trend=0.04). Conclusions: The risk of CRC may be reduced by adopting a healthy lifestyle and practicing physically activity regularly, especially among females. Consuming adequate amounts of water and healthy bowel motility could also reduce the risk of CRC.

Physical Activity and Cancer Prevention: Awareness and Meeting the Recommendations among Adult Saudis

“…Among females, a significant trend of reduction in CRC by 62% was observed with increasing the level of PA expressed in MET. They have concluded that being physically active could reduce the risk of developing CRC, especially in women (Tayyem et al, 2013). Similar findings were reported by Arafa et al (2011), where a sedentary lifestyle and a diet low in fruits and vegetables, and high in animal red meat and saturated fat, appeared to be associated with CRC among the studied Jordanian subjects (Arafa et al, 2011).…”

Awareness of Risk Factors for Cancer among Omani adults- A Community Based Study

“…The low public awareness in Oman of the importance of adopting a healthier lifestyle could be a key cause for the increasing incidence of cancer in this country (Danaei, 2005;Rahim et al, 2014). Indeed, it has been found that, developing chronic disease, including cancer decreased progressively as an individual adopted a healthier life style (Tayyem et al, 2013;Liu et al, 2014).…”

Laparoscopic Versus Open Surgery for Rectal Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials

“…With an aging population over the next decade and changing lifestyle patterns, a higher colorectal cancer incidence will be translated into (Morrison et al, 2013;Tayyem et al, 2013). In recent years, accumulating evidence indicates that laparoscopic surgery for colon carcinoma is associated with earlier postoperative recovery, lower morbidity and with equivalent long-term outcomes (Bonjer et al, 2007;Kahnamoui et al, 2007;Di et al, 2013).…”