Physical modification of carbon nanotubes with a dendrimer bearing terminal mercaptoundecahydrododecaborates (Na2B12H11S)

Yamagami, Masahiro; Tajima, Tomoyuki; Ishimoto, Kango; Miyake, Hideaki; Michiue, Hiroyuki; Takaguchi, Yutaka

doi:10.1002/hc.21467

Cited by 11 publications

(7 citation statements)

References 62 publications

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“…As a method for the highly efficient delivery of boron drugs, investigations using liposomes [ 198 ], antibody modification [ 199 ], and dendrimers [ 200 ] have been reported. Kueffer et al reported that tumor accumulation could be improved by encapsulating BSH in liposomes and improving blood retention, but since BSH also accumulated in normal cells, a strategy to add tumor cell selectivity is necessary [ 201 ] Kang et al reported that BSH was efficiently taken up by cancer cells by encapsulating it in liposomes modified with a peptide that has a high affinity for integrin αvβ3, which is highly expressed in neovascularization and GBM [ 202 ].…”

Section: Relationship Between Boron Neutron Capture Therapy (Bnct) and Boron Compoundsmentioning

confidence: 99%

A Critical Review of Radiation Therapy: From Particle Beam Therapy (Proton, Carbon, and BNCT) to Beyond

Matsumoto

Fukumitsu²,

Ishikawa

et al. 2021

JPM

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In this paper, we discuss the role of particle therapy—a novel radiation therapy (RT) that has shown rapid progress and widespread use in recent years—in multidisciplinary treatment. Three types of particle therapies are currently used for cancer treatment: proton beam therapy (PBT), carbon-ion beam therapy (CIBT), and boron neutron capture therapy (BNCT). PBT and CIBT have been reported to have excellent therapeutic results owing to the physical characteristics of their Bragg peaks. Variable drug therapies, such as chemotherapy, hormone therapy, and immunotherapy, are combined in various treatment strategies, and treatment effects have been improved. BNCT has a high dose concentration for cancer in terms of nuclear reactions with boron. BNCT is a next-generation RT that can achieve cancer cell-selective therapeutic effects, and its effectiveness strongly depends on the selective 10B accumulation in cancer cells by concomitant boron preparation. Therefore, drug delivery research, including nanoparticles, is highly desirable. In this review, we introduce both clinical and basic aspects of particle beam therapy from the perspective of multidisciplinary treatment, which is expected to expand further in the future.

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Section: Relationship Between Boron Neutron Capture Therapy (Bnct) and Boron Compoundsmentioning

confidence: 99%

A Critical Review of Radiation Therapy: From Particle Beam Therapy (Proton, Carbon, and BNCT) to Beyond

Matsumoto

Fukumitsu²,

Ishikawa

et al. 2021

JPM

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“…By making a little associate of (SWCNT-C(CO)-[O(CH2)2]2-O-metallaborane], a single world carbon nanotube functionalized with Cobalt polaroid and graphene-oxide-close-do-deca-carbonate non-hydrides [30]. When these single-walled carbon nanotubes (SWCNT's) hybrid with dendrimer (SB12)4 contain the fluorescence of NIR-I/NIR-II [46]. That will prove boron clusters can be extensively usable in BNCT.…”

Section: 54mentioning

confidence: 99%

A Mini Review on Application of Boron Neutron Capture Therapy in Cancer Treatment

Namdev

Kaur

2022

IOP Conf. Ser.: Mater. Sci. Eng.

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Nowadays, Cancer is undoubtedly a consequential and potentially life-threatening illness. In the U.S., Around 1.7 million people discerned with Cancer last year. The application of boron in cancer treatment is applicable as therapy known as Boron Neutron Capture Therapy (BNCT). It is an analeptic technique that depends on the nuclear capture and fission reaction that results in various particles such as Li, He nuclei with their kinetic energy and γ-radiation. These radiations kill the malignant cells in our body without damaging the normal tissue. Boron particles delivered selectively to only malignant cells by minimizing their concentration in normal cells. In this article, The clinical trials, clinical investigation in Different countries with a different type of Cancer as Lung, Brain, Head/Neck, Hepatic and gastrointestinal. Various delivery methods of Boron agents in the tumor cells recently developed boron delivery agents, and different techniques of their dose distribution explain. In recent years, boron compounds were applied with porphyrin, copolymers, nanoparticles, other peptides, EGRF’s, and Liposomes to intensify their killer properties toward target cancer cells. BNCT is also effectively used for the medication of various kinds of Cancers explained. The purpose of this article is to indicate the intelligible way of BNCT(Reactor-Based) for the treatment of malignant cells.

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“…为3.12, 肿瘤内滞留时间超过48 h. SWCNT还具备荧光成像性能 [212] . Yamagami等 [213] [199] ; (b) BPN示意图 [89] ; (c) Pcy示意图 [203] ; (d) MPEG-b-P(LA-co-D-Gal-MPCB)示意图 [204] (网络版彩图) . 在纳米医学的研究基础上, 含硼量丰富(约50%)的氮化硼纳米材料是非常有潜力的纳…”

Section: 碳纳米材料unclassified

Development history of boron delivery agents

Li¹,

Tu²,

Liu³

2020

Sci. Sin.-Chim

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Physical modification of carbon nanotubes with a dendrimer bearing terminal mercaptoundecahydrododecaborates (Na₂B₁₂H₁₁S)

Cited by 11 publications

References 62 publications

A Critical Review of Radiation Therapy: From Particle Beam Therapy (Proton, Carbon, and BNCT) to Beyond

A Critical Review of Radiation Therapy: From Particle Beam Therapy (Proton, Carbon, and BNCT) to Beyond

A Mini Review on Application of Boron Neutron Capture Therapy in Cancer Treatment

Development history of boron delivery agents

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