Physical performance measures in screening for reduced lean body mass in adult females with obesity

Ghoch, Marwan El; Rossi, Andrea P.; Calugi, Simona; Rubele, Sofia; Soave, Fabio; Zamboni, Mauro; Chignola, Elisa; Mazzali, Gloria; Bazzani, Paola Vittoria; Grave, Riccardo Dalle

doi:10.1016/j.numecd.2018.06.008

Cited by 20 publications

(23 citation statements)

References 24 publications

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“…Firstly, to the best of our knowledge, it is the first to assess low LBM in the Arab region and one of the few studies to assess low LBM among individuals with overweight and obesity, by taking into account ALM, weight and BMI [22]. In fact, as far as we are aware, only one study has used this definition to identify low LBM, in this case, among Italian treatment-seeking patients with obesity [13].…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, it is important to note that defining low LBM in individuals with excess weight based only on lean mass (without accounting for body mass) may be misleading, because patients with overweight and obesity tend to have a relatively high lean mass [13]. Hence, the criteria for low LBM, when based solely on this parameter, may not be met among these individuals in whom the prevalence may therefore be greatly underestimated [13].…”

Section: Introductionmentioning

confidence: 99%

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Reduced Lean Body Mass and Cardiometabolic Diseases in Adult Males with Overweight and Obesity: A Pilot Study

Khazem

Itani

Kreidieh

et al. 2018

IJERPH

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Little is known about the reduction in lean body mass (LBM) and its health consequences in overweight and in obesity, especially in males. Therefore, we aimed to assess the prevalence of low LBM in treatment-seeking adult males with overweight and obesity and the association with cardiometabolic diseases, i.e., type 2 diabetes, cardiovascular diseases and dyslipidemia. A body composition assessment was conducted by a bio-impedance analyzer (InBody 170) among a total of 110 males, of whom 72 were overweight and obese and were referred to the Outpatient Clinic in the Department of Nutrition and Dietetics at Beirut Arab University (BAU) in Lebanon, and 38 were normal-weight participants of similar ages. The participants with overweight and obesity were then categorized as being with or without low LBM. Of the sample of 72 participants, 50 (69.4%) met the criteria for reduced LBM and displayed a significantly higher prevalence of cardiometabolic diseases (i.e., type 2 diabetes, cardiovascular diseases and dyslipidemia) than those with normal LBM (36.0% vs. 9.1%; p = 0.019). Logistic regression analysis showed that low LBM increases the odds of having cardiometabolic diseases by nearly 550% (odds ratio (OR) = 5.46, 95% confidence interval (CI) = 1.31–26.39, p < 0.05) after adjusting for total fat and central adiposity. Treatment-seeking adult males with overweight and obesity displayed a great prevalence of reduced LBM, which seems to be strongly associated with cardiovascular and metabolic diseases.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Reduced Lean Body Mass and Cardiometabolic Diseases in Adult Males with Overweight and Obesity: A Pilot Study

Khazem

Itani

Kreidieh

et al. 2018

IJERPH

View full text Add to dashboard Cite

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“…Measurements were taken with the participants positioned on the scanner table with their soft tissue completely within the DXA field of view. All scans were subsequently analyzed by a single trained investigator as described elsewhere . The appendicular skeletal muscle mass (ASM) was calculated using the standard formulas .…”

Section: Methodsmentioning

confidence: 99%

Weight Cycling as a Risk Factor for Low Muscle Mass and Strength in a Population of Males and Females with Obesity

Rossi

Rubele

Calugi

et al. 2019

Obesity

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Objective: This study aimed to determine whether multiple weight cycles in adulthood are an independent predictor of lower muscle mass and reduced strength, with potential implication for sarcopenia in adults with obesity. Methods: A total of 60 males and 147 females with obesity were included, with a mean BMI of 37.9 ± 6.0 kg/m 2 and a mean age of 52.6 ± 12.4 years. Muscle strength was evaluated with handgrip and appendicular skeletal muscle mass was measured with dual-energy x-ray absorptiometry. Results: Participants were categorized into the following three groups: non-weight cyclers, mild weight cyclers, and severe weight cyclers. From a binary logistic regression that considered muscle mass categories as a dependent variable and weight cycling categories, age, and sex as independent variables, severe weight cyclers showed a 3.8-times increased risk of low muscle mass (95% CI: 1.42-10.01). Considering handgrip strength categories as a dependent variable and weight cycling categories, age, sex, and BMI as independent variables, severe weight cycling was associated with an increased risk of low muscle mass (about 6.3 times, 95% CI: 1.96-20.59). Severe weight cyclers showed a 5.2-times greater risk of developing sarcopenia. Conclusions: In adults with obesity, weight cycling is associated with lower muscle mass and strength and a greater likelihood of developing sarcopenic obesity.

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“…In the same direction, interestingly, recent studies have found a strong association between SO and impairment of physical performance (10). However, to the best of our knowledge, it is still unclear whether individuals with SO are likely to have a more sedentary lifestyle than those with obesity alone, however, if this is true, it may have significant clinical implications, especially among those seeking treatment and in the identification of SO in patients with obesity, for whom it becomes critically important to target interventions (11).…”

Section: Introductionmentioning

confidence: 77%

Association Between Reduced Daily Steps and Sarcopenic Obesity in Treatment-Seeking Adults With Obesity

et al. 2020

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Objectives: Understanding the condition that describes the coexistence of obesity and sarcopenia, termed sarcopenic obesity (SO), is becoming a scientific and clinical priority. In this study, we aimed to assess the prevalence of SO in treatment-seeking adults with obesity and investigate any potential association between SO and a sedentary lifestyle, expressed in terms of daily steps.Methods: In this cross-sectional, prospective observational study, body composition and daily steps measurements were obtained using a segmental body composition analyser (Tanita BC-418) and an Omron HJ-320 pedometer, respectively, in 111 adults of both genders with obesity (body mass index; BMI ≥ 30 kg/m 2 ), referred to the Outpatient Clinic in the Department of Nutrition and Dietetics at Beirut Arab University (BAU) in Lebanon. The participants were then categorized according to the presence of absence of SO, defined as an appendicular lean mass divided by body weight (ALM/weight) × 100%) of less than 23.40 and 29.60 in females and males, respectively.Results: Fifty-five of the 111 participants with obesity, with a mean age of 39.62 ± 16.55 years and a mean BMI of 38.05 ± 5.33 kg/m 2 met the criteria for SO and displayed a significantly higher prevalence of inactivity (<5,000 daily steps), i.e., nearly double (54.5% vs. 32.1%; p = 0.017) and they had a lower mean number of daily steps than those in the group without SO (5,279 ± 2,641 vs. 6,732 ± 2,989; p = 0.008). Linear regression analysis showed that SO is associated with a lower number of daily steps by 1,421 (β = −1421.4; −2508.9, −333.9; p = 0.011) after adjusting for age, gender employment and the presence of cardiometabolic disease.Conclusion: Sarcopenic obesity affects nearly 50% of treatment-seeking adults with obesity. Moreover, it seems to be associated with a lower number of daily steps and a sedentary lifestyle. Future studies are needed to clarify whether this may influence clinical outcomes. If this is shown to be the case, weight management programmes should incorporate additional physical activity strategies in this population.

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Physical performance measures in screening for reduced lean body mass in adult females with obesity

Cited by 20 publications

References 24 publications

Reduced Lean Body Mass and Cardiometabolic Diseases in Adult Males with Overweight and Obesity: A Pilot Study

Reduced Lean Body Mass and Cardiometabolic Diseases in Adult Males with Overweight and Obesity: A Pilot Study

Weight Cycling as a Risk Factor for Low Muscle Mass and Strength in a Population of Males and Females with Obesity

Association Between Reduced Daily Steps and Sarcopenic Obesity in Treatment-Seeking Adults With Obesity

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