We investigated the acoustic and acousto-optic parameters of cubic crystal KRS-5, which can be used in acousto-optic devices operating with optical radiation from visible to far infrared regions. The results of acoustic and acousto-optic property calculations are presented. Also, we present a possibility of obtaining optical birefringence in cubic material when external static pressure is applied to the KRS-5 crystal. We discuss in detail the results of anisotropic Bragg diffraction observation in cubic crystal in the presence of external static pressure.