Physical Properties of the Probiotic Effervescent Tablet from Tapioca and Maltodextrin Coatings

Abstract

The purpose of this study was to determine the physical properties of probiotic effervescent tablets with two different coatings that are tapioca and maltodextrin to improve water quality in shrimp farming ponds. This study used probiotics to improve the environmental quality of shrimp pond waters. Liquid probiotics from Research Institute for Coastal Aquaculture in Maros, South Sulawesi that contain Brevibacillus laterosporus. Probiotics that have been used are liquid and difficult to transport, therefore microencapsulation is carried out on liquid probiotics aimed at facilitating their distribution. The use of microencapsulating materials is to entrap or immobilize probiotic bacteria within microcapsule and to protect the bacteria during the drying process. Effervescent tablets were prepared in a dosage of 800 mg by wet granulation methods. This experiment was replicated 3 times. Tablets were evaluated for their physical properties there are mean weight, friability, hardness, disintegration time and pH. The results showed that mean weight for effervescent tablets with maltodextrin coatings was 796 mg, had a friability value 0.09%, a hardness value of 13.7 N and disintegration time of 10.68 minutes. Both probiotic effervescent tablets meet the standards pH of 7.07 and 6.67. The maltodextrin coatings was the best treatment of this study.

Efficacy of lyophilized Lactobacillus sakei as a potential candidate for the prevention of carbapenem-resistant Klebsiella infection

“…Accordingly, the L. sakei powder was packed with polyethylene material at a ratio of 1:3 to preserve its treatment e cacy. From an industrial point of view, using probiotic powder instead of bacteria culture is preferred due to the higher viability of the product during storage and the ease of use (NAKSING et al, 2019;Oktavia et al, 2020). In addition, our data showed that L. sakei powder had higher e cacy in an in vivo model than L. sakei culture.…”

Artikel Review : Formulasi Dan Evaluasi Sediaan Efervesen Herbal Sebagai Antioksidan

“…Bahan tambahan lainnya seperti pengisi, pengikat, pemanis dan lubrikan pada sediaan efervesen digunakan dengan mempertimbangkan kelarutanya dalam air. Bahan tambahan yang digunakan harus larut sempurna dalam air sehingga tidak meninggalkan residu [35]. Berdasarkan hasil telaah, pengikat yang paling banyak digunakan yaitu polivinilpirolidon (PVP) yang dianggap sebagai pengikat efektif.…”

Effect of Process Parameters, Protectants and Carrier Materials on the Survival of Yeast Cells during Fluidized Bed Granulation for Tableting

“…In general, the viability of microorganisms decreases with increasing compression stress [ 7 , 8 , 9 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 ]. However, previous data on the survival of microorganisms during tableting exist predominantly for lyophilized microorganisms [ 9 , 18 , 19 , 20 , 21 , 22 , 27 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 ] and are hardly available for fluidized bed granulated ones; however, at least some data are available for wet granulated and, e.g., oven-dried microorganisms [ 7 , 8 , 23 , 24 , 25 , 39 , 40 ]. Considering, especially, the different product structures (physical mixture vs. granules and the typically high porosity and fragility of lyophilized products), the survival during tableting needs to also be addressed for granulated microorganisms.…”