Physical Structure of Drug Dispersions in PVP Determined by Low Frequency Dielectric Spectroscopy and X-Ray Powder Diffraction

The dielectric response of four batches of lactose has been measured over a frequency range of 10(4) to 10(-2) Hz. The spectra corresponding to three of the batches were identical, while the fourth showed a marked reduction in response. This particular batch has also been reported to exhibit longer disintegration times than the other three when formulated as a tablet. The potential use of dielectric spectroscopy as a means of screening batches of pharmaceutical materials is discussed.

show abstract

Applications of low frequency dielectric spectroscopy to the pharmaceutical sciences

Craig

1992

Drug Development and Industrial Pharmacy

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Physical Structure of Drug Dispersions in PVP Determined by Low Frequency Dielectric Spectroscopy and X-Ray Powder Diffraction

Cited by 3 publications

References 1 publication

The use of dielectric analysis as a means of characterising the effects of moisture uptake by pharmaceutical glyceride bases

The use of dielectric analysis as a means of characterising the effects of moisture uptake by pharmaceutical glyceride bases

Characterization of the variation between batches of Fast-Flo lactose using low frequency dielectric spectroscopy

Applications of low frequency dielectric spectroscopy to the pharmaceutical sciences

Contact Info

Product

Resources

About