Physical Therapy–Based Early Intervention in Limb-Girdle Muscular Dystrophy

Kunti, Chetna; Ryain, Aamreen; Dogra, Pooja; Ghosh, Amrita; Parab, Shrutika

doi:10.1007/s12098-022-04444-1

Cited by 2 publications

(3 citation statements)

References 2 publications

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“…The spectrum of conditions encapsulated by this subset ranges from severe and fatal congenital muscular dystrophies with onset in infancy to mild forms of limb and girdle weakness with onset in adulthood and minimal respiratory compromise. The list and classification of muscular dystrophies are undergoing near-constant revision, based largely on new insights from genetics and molecular medicine [3].These advances are reflected in the development of new therapeutic approaches, some of which have already led to clinical trials in the dystrophinopathies and limb-girdle dystrophies4.We present a case of muscular dystrophy of the waist and limbs and, based on the physical and neurological examination, we suggest possibilities for rehabilitation treatment [4].…”

Section: Discussionmentioning

confidence: 99%

Distrofia muscular de cinturas e fisioterapia: atualização e relato de caso

Orsini,

Mesquita,

Freitas

et al. 2024

Fisioter Bras

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O termo distrofia muscular de cinturas (DMC) foi introduzido para delinear uma forma distinta de distrofia muscular com fraqueza predominantemente proximal nas extremidades superiores e inferiores. PAS, 71 anos, sexo masculino, aposentado, diabéticos e hipertenso. Ele relata que o quadro clínico iniciou em meados de 2010 com queixas relacionadas à atrofia da cintura escapular e região da coxa. “Ao me olhar no espelho comecei a perceber que estava perdendo músculos nos ombros”. O início do quadro clínico se arrastou, ainda com formato muscular próximo ao normal para realização das atividades diárias. Ele ressalta que a região cervical o incomoda bastante, principalmente pela posição inclinada em que se encontra. Neste caso clínico apresentamos avaliações neurológicas e funcionais, bem como exames complementares que auxiliam na detecção de DMC. Novos estudos, abrangendo um número maior de pacientes com miopatia de cintura e membros, são necessários. Acreditamos que a melhor forma de reabilitação para esse grupo de miopatias é não buscar danos por uso excessivo e, sem dúvida, trabalhar em busca de função e não principalmente de força.

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Section: Discussionmentioning

confidence: 99%

Distrofia muscular de cinturas e fisioterapia: atualização e relato de caso

Orsini,

Mesquita,

Freitas

et al. 2024

Fisioter Bras

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“…Strenuous or demanding exercises may not be suitable for those with LGMD since they could weaken them and harm their muscles. When considering an exercise program for a person with calpaniopathy, it is imperative to see a medical expert with experience treating patients with muscular dystrophy [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…Overtraining or prolonged exercise (high-intensity training) may be harmful, raising the risk of accidents and falls due to muscle weakness and potentially causing damage to the muscles. Exercise programs should be tailored to each individual and carried out under supervision to avoid fatigue and hasten the condition's slow progression [11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Management of a 25-Year-Old Female Patient With Limb-Girdle Muscular Dystrophy With Physiotherapy: A Case Report

Nandanwar,

Udhoji,

Raghuveer

2024

Cureus

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Limb-girdle muscular dystrophy (LGMD) is a collection of neuromuscular diseases that develop gradually and are rare, genetically, and clinically diverse. The weakness in muscles affecting the shoulder and pelvic girdles is a defining feature of LGMD. Calpainopathy is another name for limb-girdle muscular dystrophy type 2A (LGMD2A). Limb-girdle muscular dystrophy type 2A results from alterations in the calpain-3 (CAPN3) gene, which results in a CAPN3 protein shortage. Gower's sign is most commonly found in LGMD2A. The prevalence ranges from one person in every 14,500 to one in every 123,000. We present a case of a 25-year-old hypotensive female patient who complained of weakness in all four limbs and easy fatigue with a positive Gower’s sign. For subsequent management, the neurologist referred the patient to the physical therapy department. The physical therapy goals included enhanced muscle strength, increased joint mobility, reduced fatigue, normalizing gait, and building dynamic balance and postural stability. Diagnosing LGMD clinical variability is important, emphasizing the importance of precise subtype identification and tailoring therapy. Tackling specific muscular deficits and functional restrictions emerges as a critical component in the holistic care of LGMD by physiotherapists. Continuous monitoring and evaluation using appropriate scales and measurements are essential for tracking performance and tailoring treatment strategies. Regular follow-up consultations with the physiotherapist are needed to identify changes in an individual's health and alter the treatment plan accordingly.

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Physical Therapy–Based Early Intervention in Limb-Girdle Muscular Dystrophy

Cited by 2 publications

References 2 publications

Distrofia muscular de cinturas e fisioterapia: atualização e relato de caso

Distrofia muscular de cinturas e fisioterapia: atualização e relato de caso

Management of a 25-Year-Old Female Patient With Limb-Girdle Muscular Dystrophy With Physiotherapy: A Case Report

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