Physical therapy interventions, other than general physical exercise interventions, in children and adolescents before, during and following treatment for cancer

Оцінка Особливостей Перебігу Онкогематологічних Захворювань У Дітей Різного Віку

“…Поширеність злоякісних пухлин у дітей різного віку швидко збільшується, що вказує на актуальність цієї проблеми. Діти та підлітки, у яких діагностовано розвиток новоутворення, мають високий ризик виникнення серйозних побічних ефектів як від самої патології, так і від лікування раку [1]. Серед онкологічних патологій найпоширенішими є онкогематологічні захворювання, до яких входять гострі і хронічні лейкози, лейкемія, лімфома Ходжкіна, мієломна хвороба (мієлодисплазія) [2,3].…”

Physical modulation of mesenchymal stem cell exosomes: A new perspective for regenerative medicine

“…Physical factors can be categorized into two aspects: one pertains to the physical characteristics of internal microenvironment, such as substrate stiffness and topography, 26–29 while the other involves external physical stimulations, including mechanical strain, ultrasound, laser, electrical stimulation and other stimuli 30–34 . Although intense physical stimulation is a major factor contributing to tissue damage, 35,36 it can be widely used as a therapeutic approach in a variety of diseases if the parameters are properly adjusted 37–40 . Previous studies have demonstrated that exosomes are highly sensitive to physical factors 41,42 .…”

“… 30 , 31 , 32 , 33 , 34 Although intense physical stimulation is a major factor contributing to tissue damage, 35 , 36 it can be widely used as a therapeutic approach in a variety of diseases if the parameters are properly adjusted. 37 , 38 , 39 , 40 Previous studies have demonstrated that exosomes are highly sensitive to physical factors. 41 , 42 Appropriate stimuli can induce beneficial changes in MSC‐Exo, thus enhancing their impact on the microenvironment.…”

Tailored Psychoeducational Home Interventions for Children with a Chronic Illness: Families’ Experiences

“…Illnesses and their treatments can cause significant psychosocial stressors and side effects that can negatively impact the quality of life of both the child and their family; additionally, they may hinder the child’s ability to participate in common social and educational activities that are otherwise important for healthy development, such as play, sports, and school ( Ospina et al, 2021 ). However, psychoeducational interventions and physical and psychological therapies designed to support children and their families in managing the psychosocial consequences of chronic diseases and their treatments can alleviate such negative side effects ( Barlow & Ellard, 2004 ; Yang et al, 2022 ).…”