Objective To observe the effect of intervention of periodic resistance training on obese patients with type 2 diabetic nephropathy.
Methods A total of 60 obese patients with type 2 diabetic nephropathy were randomized into resistance training group and aerobic exercise group (30 patients each group) for observing the changes of blood glucose, body weight, blood lipid, insulin resistance, serum creatinine, urinary microalbumin, urinary albumin excretion rate calculated by urinary creatinine, and glomerular filtration rate after 12 weeks of intervention, and relevant significance as well. The number of patients with hypoglycemia during the intervention was also recorded.
ResultsAfter 12 weeks of intervention, the weight, BMI, Waist, TG, TC, LDL, HDL, FBG, FINS, HbA1c and urinary albumin excretion rate were decreased and glomerular filtration rate was increased in both groups (P < 0.05), but the effect was more significant in the resistance training group.
Conclusion For obese patients with type 2 diabetic nephropathy, periodic resistance training can not only control their body weight, blood glucose and blood lipid, but also improve their urinary albumin excretion rate, glomerular filtration rate, and kidney damage.