Physical work capacity with rate responsive ventricular pacing (VVIR) versus dual chamber pacing (DDD) in patients with normal and diminished left ventricular function

Frielingsdorf, Jürgen; Dür, Peter; Gerber, A; Vuilliomenet, André; Bertel, Osmund

doi:10.1016/0167-5273(95)02308-j

Cited by 9 publications

(6 citation statements)

References 36 publications

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“…Frielingsdorf et al 22 showed that patients with normal LV function may profit most from preserved AV synchrony (VDD vs VVIR) as shown by the higher maximum uptake on exercise, and conclude that rate responsive single‐chamber pacemakers largely enable the same work capacity as dual‐chamber pacemakers in patients with high‐degree AV block.…”

Section: Discussionmentioning

confidence: 99%

“…Resting plasma concentrations of atrial natriuretic peptide were raised in complete heart block and were restored to normal by DDD pacing but not by VVIR pacing. 21 Frielingsdorf et al 22 showed that patients with normal LV function may profit most from preserved AV synchrony (VDD vs VVIR) as shown by the higher maximum uptake on exercise, and conclude that rate responsive single-chamber pacemakers largely enable the same work capacity as dual-chamber pacemakers in patients with high-degree AV block.…”

Section: Ddd Versus Vvir In Elderly Patientsmentioning

confidence: 99%

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DDD versus VVIR Pacing in Patients, Ages 70 and Over, with Complete Heart Block

Ouali

Neffeti

Ghoul

et al. 2009

Pacing and Clinical Electrophysiology

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Section: Discussionmentioning

confidence: 99%

Section: Ddd Versus Vvir In Elderly Patientsmentioning

confidence: 99%

DDD versus VVIR Pacing in Patients, Ages 70 and Over, with Complete Heart Block

Ouali

Neffeti

Ghoul

et al. 2009

Pacing and Clinical Electrophysiology

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“…Further, the contribution of the atrial kick may change during exercise. Most,13 14 25but not all,26 studies in patients with artificial pacemakers suggest that the increase in ventricular rate during exercise is more important to cardiac output than atrial contraction, and this may be particularly true for patients with systolic left ventricular dysfunction 27. On the other hand, restoration of atrial contraction has also been shown to parallel5 or to precede6 the improvement of peak V˙O 2 after cardioversion; the lower peak heart rate after cardioversion suggests that intact atrial functioning yields a higher stroke volume during exercise, and thus increases exercise capacity.…”

Section: Discussionmentioning

confidence: 99%

Atrial fibrillation is associated with a lower exercise capacity in male chronic heart failure patients

Pardaens¹,

Cleemput

Vanhaecke

et al. 1997

Heart

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Objective-To study the influence of atrial fibrillation on peak oxygen uptake (peak ṼO 2 ) in chronic heart failure. An unfavourable eVect of atrial fibrillation has been shown in several patient populations, but the results have not been consistent in chronic heart failure. Methods-Data were analysed from male heart transplant candidates who were able to perform graded bicycle ergometry until exhaustion with respiratory gas analysis and measurement of heart rate. Patients in atrial fibrillation (n = 18) were compared with patients in sinus rhythm (n = 93). Results-Age, weight, height, and aetiology of chronic heart failure did not diVer significantly between the two groups. Cardiac catheterisation at supine rest showed that heart rate was comparable, but that stroke volume and cardiac output were lower (p < 0.05) in atrial fibrillation. Systolic and diastolic left ventricular function, assessed by radionuclide angiography at rest, were not significantly diVerent. Peak ṼO 2 (mean (SD): 13.8 (3.6) v 17.1 (5.6) ml/kg/min; p < 0.01) and peak work load (78 (27) v 98 (36) W; p < 0.05) were lower in the patients with atrial fibrillation, though respiratory gas exchange ratio and Borg score were similar in the two groups. Patients with atrial fibrillation had a higher heart rate sitting at rest before exercise (93 (16) v 84 (16) beats/min) and at peak eVort (156 (23) v 140 (25) beats/min) (p < 0.05). Conclusions-Atrial fibrillation is associated with a 20% lower peak ṼO 2 in patients with chronic heart failure, suggesting that preserved atrial contraction or a regular rhythm, or both, are critical to maintain cardiac output and exercise performance.

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“…The lean‐fat ratio was estimated by skinfold thickness measurements (Sohlstrom & Forsum, 1997). Maximum oxygen uptake (VO 2 max) was also measured in all subjects by spiroergometry at a respiratory quotient of 1.1. during a treadmill exercise test (Frielingsdorf et al ., 1995).…”

Section: Mean (±Sd) Plasma Oestradiol Prolactin Total Testosteronementioning

confidence: 99%