Physicians’ responses to computerized drug–drug interaction alerts for outpatients

Pharmacogenomics‐Based Point‐of‐Care Clinical Decision Support Significantly Alters Drug Prescribing

“…As with any clinical innovation, the true utility of an implementation intervention is measured by physician adoption and user response(22). For example, in a study examining physician responses to interruptive drug-drug interaction alerts, 93% were overridden or ignored(23). Underlying causes of physician reluctance to follow clinical guidance include limitations in awareness, lack of agreement, and clinical inertia(24).…”

Decrease in use of contraindicated drugs with automated alerts in children

“…According to prior research, the incidence of drug–drug interactions and the rate of alert overrides rate varied by admitting department at a tertiary teaching hospital in Korea . Similarly, the alert override rate varied by clinical specialty at a teaching hospital in Taiwan …”

An automated technique to identify potential inappropriate traditional Chinese medicine (TCM) prescriptions

“…However, we did not find any studies that indicated how to select threshold to detect appropriateness of TCM prescription. Furthermore, because there were already many studies reported about high overridden rate for reminders or alerts fatigue of CDSS, it would decrease the effectiveness of the CDSS . The objective of this study was to provide the correct reminder for potential inappropriate prescription; it has potential to adjust threshold to improve NPV.…”