Physicians' Undecided Attitudes Toward Posthumous Reproduction: Fertility Preservation in Cancer Patients with a Poor Prognosis

Quinn, Gwendolyn P.; Knapp, Caprice; Malo, Teri L.; McIntyre, Jessica; Jacobsen, Paul B.; Vadaparampil, Susan T.

doi:10.1016/j.suponc.2011.09.006

Cited by 18 publications

(16 citation statements)

References 32 publications

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“…The psycho-social impact of cancer-related infertility is often underestimated by oncologists, surgeons, and gynecologists. 15 The present survey, with a 21% response rate, presents a participation rate similar to those reported for other surveys. 16 Our survey showed that half of all participating pediatric EBMT centers had a program in which FP counseling was an integral part of patient care.…”

Section: Discussionsupporting

confidence: 83%

Fertility preservation practices in pediatric and adolescent cancer patients undergoing HSCT in Europe: a population-based survey

Diesch

Rovó

Weid

et al. 2017

Bone Marrow Transplant

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Chemotherapy and irradiation can affect the gonads, leading to impairment of pubertal development and/or infertility. Fertility preservation (FP) is therefore a crucial endeavor in hematopoietic stem cell transplantation (HSCT) because of the severe impact of infertility on the quality of life of long-term survivors. Despite the existence of different international guidelines, FP counseling and procedures are not routinely implemented as part of patient care. We present herein a survey conducted by the Pediatric Working Party of the European Society for Blood and Marrow Transplantation (EBMT), which aims to analyze and compare different FP practices for children and adolescents across EBMT centers in 2013. A total of 177 pediatric centers reporting to the EBMT were contacted; of this number, 38 centers (21%) located in 16 different countries responded. These centers reported 834 patients receiving HSCT in 2013 (73% prepubertal), corresponding to 22% of all children (n=3789) undergoing HSCT in EBMT reporting centers. Overall, 39% of the reported patients received counseling and 29% received an FP procedure. The increased need for FP programs, extended education for patient-care teams, and more personal resources and funding emerged from this survey as pivotal factors necessary to support and implement such programs.

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Section: Discussionsupporting

confidence: 83%

Fertility preservation practices in pediatric and adolescent cancer patients undergoing HSCT in Europe: a population-based survey

Diesch

Rovó

Weid

et al. 2017

Bone Marrow Transplant

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“…Another challenge is discussing what will happen with preserved sperm or ova in case of death. Posthumous reproduction is a field with many legal and ethical problems that trouble oncologists [19]. In a study by Schover et al, 60 % of young cancer patients wanted to have a child even if they were to die young.…”

Section: Patient Factorsmentioning

confidence: 99%

Patient-Physician Communication and Knowledge Regarding Fertility Issues from German Oncologists’ Perspective—a Quantitative Survey

Buske¹,

Sender

Richter

et al. 2015

J Canc Educ

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Many people diagnosed with haematologic malignancies are of child-bearing age. Typical treatment courses pose a high risk of infertility, and a lot of people affected by this are in the midst of starting or growing their families. Thus, it is crucial that they are well informed about fertility preservation options and can discuss these with an oncologist early on in the development of their treatment plans. Unfortunately, however, this does not always happen. One hundred twenty oncologists from 37 German adult clinical facilities were surveyed regarding their discussions with young patients about fertility, family planning, and fertility preservation. Almost all of them said that they consider fertility preservation to be an important issue. They also reported several factors as having an influence on the likelihood and practicability of discussing these subjects. Most knew about the existence of cryoconservation of germ cells and the use of GnRH analogues (95 %), but only half of them claimed to have a thorough understanding of these options. Many said they would like to learn more about this and that informational brochures could be helpful. Even though many oncologists do have good working knowledge of the subject, patients of reproductive age are not yet consistently given comprehensive information about the options available to them. To improve oncologists' knowledge of reproductive medicine, cooperation with fertility specialists should be facilitated, and informational leaflets should be made available both to patients and their medical care providers.

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“…Although families may be able to support the initial tissue harvesting, cryopreservation and storage for several years, they may not be able to afford preservation until the patient desires childbearing [65]. The utility of investing financially into an experimental procedure may be questionable.…”

Section: Ethical Legal and Social Issuesmentioning

confidence: 99%

Fertility Preservation for Prepubertal Girls: Update and Current Challenges

Resetkova

Hayashi

Kolp

et al. 2013

Curr Obstet Gynecol Rep

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With increasing rates of diagnosis of childhood cancers and the evolution of more effective treatment options resulting in prolonged life spans, fertility preservation counseling is an integral component of the discussion at the time of diagnosis of childhood cancers. The primary fertility preservation option that exists for prepubertal girls is ovarian tissue cryopreservation. Although ovarian tissue cryopreservation is still considered to be experimental in nature, live births have resulted from orthotopic tissue transplantation. Fertility preservation should be offered to all prepubertal girls at high-risk for premature ovarian failure as a result of gonadotoxic treatment. Ethical and legal questions surrounding these issues must be considered as more and more pediatric patients pursue fertility preservation.

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Physicians' Undecided Attitudes Toward Posthumous Reproduction: Fertility Preservation in Cancer Patients with a Poor Prognosis

Cited by 18 publications

References 32 publications

Fertility preservation practices in pediatric and adolescent cancer patients undergoing HSCT in Europe: a population-based survey

Fertility preservation practices in pediatric and adolescent cancer patients undergoing HSCT in Europe: a population-based survey

Patient-Physician Communication and Knowledge Regarding Fertility Issues from German Oncologists’ Perspective—a Quantitative Survey

Fertility Preservation for Prepubertal Girls: Update and Current Challenges

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