Physico-chemical characteristic and biological activity of the supramolecular complex of glycyram with b-cyclodextrin

Association of aescin with β- and γ-cyclodextrins studied by DFT calculations and spectroscopic methods

“…Currently, CDs are being used to afford non-toxic aqueous formulations with antitumoural single triterpenoids such as oleanoic [ 17 – 19 ], ursolic [ 18 – 19 ] and betulinic [ 18 , 20 – 22 ] acids. Ammonium glycyrrhizinate or glyciram (from licorice roots), sold in Russia and Japan as a natural anti-inflammatory, antiallergic and anti-spasmodic medicine, was also reported to become more stable against epoxidation upon inclusion into β-CD, thus gaining increased shelf-life [ 23 – 24 ].…”

Inclusion Complex Formation of β-Cyclodextrin with the Nonsteroidal Anti-inflammatory Drug Flufenamic Acid: Computational Study

“…The most known and studied members of this family are α-CD, β-CD and γ-CD which can complex a broad array of organic molecules through host-guest inclusion systems. CDs are widely used in various fields such as food technology, pharmaceutical, cosmetics and textile industry, [7][8][9][10][11][12][13] their cone-shaped structures enclose a hydrophilic external surface and a relatively hydrophobic inner cavity, resulting in the ability of CDs to encapsulate small hydrophobic organic guest molecules.…”