Aluminium and magnesium based metal matrix nanocomposites (MMNC) with ceramic nano-reinforcements promise low weight with high durability and superior strength, desirable properties in aerospace, automobile and other applications. However, nano-particle agglomerations lead to adverse effects on final properties: large-size clusters no longer act as dislocation anchors, but instead become defects; the resulting particle distribution will be uneven, leading to inconsistent properties. To prevent agglomeration and to break up clusters, ultrasonic processing is used via an immersed sonotrode, or alternatively via electromagnetic vibration. A study of the interaction forces holding the nano-particles together shows that the choice of adhesion model significantly affects estimates of break-up force and that simple Stokes drag due to stirring is insufficient to break up the clusters. The complex interaction of flow and co-joint particles under a high frequency external fields (ultrasonic, electromagnetic) is addressed in detail using a discrete-element method (DEM) code to demonstrate the effect of these fields on deagglomeration.