Physico-mechanical and in vitro characterization of electrically conductive electrospun nanofibers of poly urethane/single walled carbon nano tube by great endothelial cells adhesion for vascular tissue engineering

Tondnevis, Farbod; Keshvari, Hamid; Mohandesi, Jamshid Aghazadeh

doi:10.1007/s10965-019-1916-0

Cited by 16 publications

(7 citation statements)

References 83 publications

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“…Regarding the cytotoxic effect of nano chitosan particles 0.2mg/ml showed the least cytotoxic effect on cells. 32,33 For all groups, a solution of 17% EDTA was used as its chelating effect promotes the release of dentinderived growth factors that were previously embedded into dentin during the process of dentinogenesis 34 . These growth factors such as transforming growth factor-beta1 (TGF-b) , dentin sialoprotein (DSP), platelet derived growth factors (PDGF), vascular endothelial growth factor (VEGF), placenta growth factor (PlGF) and fibroblast growth factor (FGF2), have been shown to stimulate proliferation, survival, and differentiation of dental stem cells [35][36][37] .…”

Section: Discussionmentioning

confidence: 99%

Assessment of the Survival and Sensibility of Mature Anterior Teeth with Periapical Lesion after One Step Regenerative Approach Using Different Disinfection Maneuvers : A Randomized Clinical Trial

Mohamed Mohsen Abielhassan,

Nihal Ezzat Sabet,

Alaa Abdelsalam El Baz

2021

IJPHRD

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Aim: evaluate outcomes of single visit regenerative endodontic procedures using conventional irrigation protocol in comparison to LASER disinfection in comparison to 0.2% Nano Chitosan irrigating solution for treatment of necrotic mature anterior teeth with periapical lesions.Methodology: 45 patients were recruited in this trial. Preoperative standardized cone beam computed tomography (CBCT) was performed for the patients after fulfillment of inclusion criteria.After complete diagnostic steps and signing of consent forms and performance of access cavity preparation,patients were randomly distributed into three groups with three disinfection maneuvers:1. Group A (Intervention 1)final disinfection using Low Power Diode LASER disinfection. Group B (Intervention 2 ) final rinseusing 0.2% Nano Chitosan irrigation disinfection in a side perforated needle.3. Group C (Control) conventional irrigation protocol using 1.25% sodium hypochlorite irrigating solution and 17% EDTA only.Platelet rich fibrin was packed inside the root canals followed by collagen plug and Biodentin. Teeth were restored using resin modified glass ionomer.Patients were recalled for regular follow ups at 6 and 12 months. Patients were examined for survival of treated teeth and any inflammatory signs or symptoms. All samples were tested for sensibility. All data were statistically analyzed.Results: Single visit regenerative endodontics possessed an overall percentage of success 95.5% in all groups in terms of survival of treated teeth. Regarding sensibility nano chitosan also possessed the highest percentage of cases regaining sensitivity by 73.3% followed by laser group 67.7% followed by the control group with 46.7% also with no statistical significant difference between all groups. Conclusion:Within limitations of this study single visit regenerative endodontics can be applied to cases with necrotic pulps and periapical lesions where thorough disinfection is recommended in cases of single visit approach to ensure maximum elimination of bacterial cells from root canal hindering successful

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Section: Discussionmentioning

confidence: 99%

Assessment of the Survival and Sensibility of Mature Anterior Teeth with Periapical Lesion after One Step Regenerative Approach Using Different Disinfection Maneuvers : A Randomized Clinical Trial

Mohamed Mohsen Abielhassan,

Nihal Ezzat Sabet,

Alaa Abdelsalam El Baz

2021

IJPHRD

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“…Nanotechnology has favorable circumstances in the engineering of blood vessel tissue. The preparation of a multifunctional hybrid material in a scaffold form for vascular tissue engineering was investigated by combining the special mechanical, electrical, and biochemical characters of SWNTs with electrospun PU nanofibers [ 143 ]. Homogeneous dispersions and SWNT interactions with polyurethane chains refined the mechanical behavior of the composite, such as tensile strength and Young’s modulus, which may mimic the natural properties of the blood vessel.…”

Section: Synthetic Polymers Based On Carbon Materialsmentioning

confidence: 99%

Recent Biomedical Applications of Coupling Nanocomposite Polymeric Materials Reinforced with Variable Carbon Nanofillers

et al. 2023

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The hybridization between polymers and carbon materials is one of the most recent and crucial study areas which abstracted more concern from scientists in the past few years. Polymers could be classified into two classes according to the source materials synthetic and natural. Synthetic polymeric materials have been applied over a floppy zone of industrial fields including the field of biomedicine. Carbon nanomaterials including (fullerene, carbon nanotubes, and graphene) classified as one of the most significant sources of hybrid materials. Nanocarbons are improving significantly mechanical properties of polymers in nanocomposites in addition to physical and chemical properties of the new materials. In all varieties of proposed bio-nanocomposites, a considerable improvement in the microbiological performance of the materials has been explored. Various polymeric materials and carbon-course nanofillers were present, along with antibacterial, antifungal, and anticancer products. This review spots the light on the types of synthetic polymers-based carbon materials and presented state-of-art examples on their application in the area of biomedicine.

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“…The synthesis of the first biomedical grade polyether PU showed suitable mechanical properties, including resistance to flex-fatigue, high elasticity modulus, and good stability over long implantations [ 41 ]. Unfortunately, it has been reported that PU has low cell interaction and bio-stability in the long-term in in-vivo conditions [ 42 ]. In temperatures around 10–20 °C below the melting point of the medical-grade TPU, the hard block morphology continues to evolve to produce a reversible improvement in shear viscosity and elasticity of the TPU by increasing the time of synthesis.…”

Section: Applications Of Pu-based Scaffoldsmentioning

confidence: 99%

A critical review of fibrous polyurethane-based vascular tissue engineering scaffolds

Karkan

Banimohamad-Shotorbani

Saghati

et al. 2022

J Biol Eng

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Certain polymeric materials such as polyurethanes (PUs) are the most prevalent class of used biomaterials in regenerative medicine and have been widely explored as vascular substitutes in several animal models. It is thought that PU-based biomaterials possess suitable hemo-compatibility with comparable performance related to the normal blood vessels. Despite these advantages, the possibility of thrombus formation and restenosis limits their application as artificial functional vessels. In this regard, various surface modification approaches have been developed to enhance both hemo-compatibility and prolong patency. While critically reviewing the recent advances in vascular tissue engineering, mainly PU grafts, this paper summarizes the application of preferred cell sources to vascular regeneration, physicochemical properties, and some possible degradation mechanisms of PU to provide a more extensive perspective for future research.

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Physico-mechanical and in vitro characterization of electrically conductive electrospun nanofibers of poly urethane/single walled carbon nano tube by great endothelial cells adhesion for vascular tissue engineering

Cited by 16 publications

References 83 publications

Assessment of the Survival and Sensibility of Mature Anterior Teeth with Periapical Lesion after One Step Regenerative Approach Using Different Disinfection Maneuvers : A Randomized Clinical Trial

Assessment of the Survival and Sensibility of Mature Anterior Teeth with Periapical Lesion after One Step Regenerative Approach Using Different Disinfection Maneuvers : A Randomized Clinical Trial

Recent Biomedical Applications of Coupling Nanocomposite Polymeric Materials Reinforced with Variable Carbon Nanofillers

A critical review of fibrous polyurethane-based vascular tissue engineering scaffolds

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