Physicochemical and antimicrobial assessment of Iranian Propolis gathered in Qazvin province

Samiee-Rad, Fatemeh; Gheibi, Nematollah

doi:10.31989/ffhd.v10i2.689

Cited by 3 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this research, TPC and TFC and some biological activities (antioxidant, antimicrobial, and anticholinesterase) of 12 propolis samples collected from various geographical regions of Iran were investigated. The antibacterial and antioxidant properties of one or a few limited Iranian propolis samples have been previously studied (Afrouzan et al, 2018; Jafarzadeh Kashi et al, 2011; Mohammadzadeh et al, 2007; Rezvani et al, 2018; Samieerad & Gheibi, 2020). This research is therefore the first survey on the evaluation of the biological properties of several Iranian propolis samples and the first study on the anticholinesterase (anti‐AChE and anti‐BuChE) activity of Iranian propolis.…”

Section: Resultsmentioning

confidence: 99%

Correlation between total phenolic and flavonoid contents and biological activities of 12 ethanolic extracts of Iranian propolis

Fathi Hafshejani

Lotfi

Rezvannejad

et al. 2023

Food Science & Nutrition

View full text Add to dashboard Cite

Propolis is a resinous substance produced by honey bees that is very popular as a natural remedy in traditional medicine. The current research is the first study on the biological properties of ethanolic extracts of propolis (EEP) from several different regions (12) of Iran. Total phenolic and flavonoid contents (TPC and TFC) of Iranian EEPs were variable between 26.59-221.38 mg GAE/g EEP and 4.8-100.03 mg QE/g EEP. The DPPH scavenging assay showed all the studied EEP samples, except for the sample with the lowest TPC and TFC (P6), have suitable antioxidant activity. All the EEPs inhibited both cholinesterase enzymes (acetylcholinesterase: AChE, butyrylcholinesterase: BuChE) but most of them exhibited a distinct selectivity over BuChE.Evaluation of the antibacterial activity of the EEP samples using four pathogenic bacteria (B. cereus, S. aureus, A. baumannii, and P. aeruginosa) demonstrated that the antibacterial properties of propolis are more effective on the gram-positive bacterium.Spearman correlation analysis showed a strong positive correlation between TPC and TFC of the Iranian EEPs and their antioxidant, anticholinesterase, and antibacterial activities. Considering that there is ample evidence of anticholinesterase activity of flavonoids and a significant correlation between the anticholinesterase activity of the studied Iranian EEPs and their total flavonoid content was observed, the interaction of 17 well-known propolis flavonoids with AChE and BuChE was explored using molecular docking. The results indicated that all the flavonoids interact with the active site gorge of both enzymes with high affinity. Summing up, the obtained results suggest that Iranian propolis possesses great potential for further studies.

show abstract

Section: Resultsmentioning

confidence: 99%

Correlation between total phenolic and flavonoid contents and biological activities of 12 ethanolic extracts of Iranian propolis

Fathi Hafshejani

Lotfi

Rezvannejad

et al. 2023

Food Science & Nutrition

View full text Add to dashboard Cite

show abstract

Biodegradable films incorporating Malaysian stingless bee propolis: Development, characterization, and potential for food packaging

Hanapiah,

Salleh,

Johari

et al. 2024

Applied Food Research

View full text Add to dashboard Cite

Perspectives for Uses of Propolis in Therapy against Infectious Diseases

Salatino

2022

Molecules

View full text Add to dashboard Cite

Propolis has gained wide popularity over the last decades in several parts of the world. In parallel, the literature about propolis composition and biological properties increased markedly. A great number of papers have demonstrated that propolis from different parts of the world is composed mainly of phenolic substances, frequently flavonoids, derived from plant resins. Propolis has a relevant role in increasing the social immunity of bee hives. Experimental evidence indicates that propolis and its components have activity against bacteria, fungi, and viruses. Mechanisms of action on bacteria, fungi, and viruses are known for several propolis components. Experiments have shown that propolis may act synergistically with antibiotics, antifungals, and antivirus drugs, permitting the administration of lower doses of drugs and higher antimicrobial effects. The current trend of growing resistance of microbial pathogens to the available drugs has encouraged the introduction of propolis in therapy against infectious diseases. Because propolis composition is widely variable, standardized propolis extracts have been produced. Successful clinical trials have included propolis extracts as medicine in dentistry and as an adjuvant in the treatment of patients against COVID-19. Present world health conditions encourage initiatives toward the spread of the niche of propolis, not only as traditional and alternative medicine but also as a relevant protagonist in anti-infectious therapy. Production of propolis and other apiary products is environmentally friendly and may contribute to alleviating the current crisis of the decline of bee populations. Propolis production has had social-economic relevance in Brazil, providing benefits to underprivileged people.

show abstract

Physicochemical and antimicrobial assessment of Iranian Propolis gathered in Qazvin province

Cited by 3 publications

References 23 publications

Correlation between total phenolic and flavonoid contents and biological activities of 12 ethanolic extracts of Iranian propolis

Correlation between total phenolic and flavonoid contents and biological activities of 12 ethanolic extracts of Iranian propolis

Biodegradable films incorporating Malaysian stingless bee propolis: Development, characterization, and potential for food packaging

Perspectives for Uses of Propolis in Therapy against Infectious Diseases

Contact Info

Product

Resources

About