“…According to previous information, the investigation published around Roselle's calyx is focused on its watery infusion characteristics (Christian & Jackson, 2009;Chumsri, Sirichote, & Itharat, 2008;Domínguez-López et al, 2008;Du & Francis, 1973;Herrera-Arellano, Flores-Romero, Chávez-Soto, & Tortoriello, 2004;Mourtzinos et al, 2008;Nnam & Onyeke, 2003;Tsai, McIntosh, Pearce, Camden, & Jordan, 2002;Wróbel, Wróbel, & ColungaUrbina, 2000), ethanolic infusions (Ali, Wabe, & Blunden, 2005;Alobo & Offonry, 2009;Mounigan & Badrie, 2007) and hydrophobic models as well (Tee, Yusof, & Mohamed, 2002). The intestinal absorption and the therapeutic effect of its functional isolated and purified molecules have been widely documented (Amos et al, 2003;Essa & Subramanian, 2009;Fouda, Daba, & Dahab, 2007;Frank et al, 2005;Hou, Tong, Terahara, Luo, & Fuji, 2005;Miyazawa Nakagawa, Kudo, Muraishi, & Someya, 1999).…”