Physicochemical characterization of a high molecular weight bioactive β-d-glucan from the fruiting bodies of Ganoderma lucidum

Liu, Yanfang; Zhang, Jingsong; Tang, Qingjiu; Yang, Yan; Guo, Qingbin; Wang, Qi; Wu, Di; Cui, Steve W.

doi:10.1016/j.carbpol.2013.10.024

Cited by 106 publications

(50 citation statements)

References 43 publications

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“…On the other hand, higher M w values were reported for yeast ␤-glucans, such as those extracted from G. lucidum (3.75 × 10 6 ) (Liu et al, 2014) (Table 3).…”

Section: Molecular Weight Analysis By Size Exclusion Chromatography (mentioning

confidence: 92%

Chitin–glucan complex production by Komagataella pastoris : Downstream optimization and product characterization

Farinha

Duarte

Pimentel

et al. 2015

Carbohydrate Polymers

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“…On the other hand, higher M w values were reported for yeast ␤-glucans, such as those extracted from G. lucidum (3.75 × 10 6 ) (Liu et al, 2014) (Table 3).…”

Section: Molecular Weight Analysis By Size Exclusion Chromatography (mentioning

confidence: 92%

Chitin–glucan complex production by Komagataella pastoris : Downstream optimization and product characterization

Farinha

Duarte

Pimentel

et al. 2015

Carbohydrate Polymers

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“…The active ingredients of Ganoderma lucidum , extracted using hot water or ethanol, include polysaccharides [3–5], proteins [6,7] and ganoderic acid [8,9]. These ingredients can be effective in the treatment of cancer, hypertension and viral infections, since numerous reports have indicated that Ganoderma lucidum has anti-tumor [10–12], anti-aging [13,14], immune system-enhancing, [15,16] and anti-hypertension [16–18] activities.…”

Section: Introductionmentioning

confidence: 99%

Intraspecific Variation and Phylogenetic Relationships Are Revealed by ITS1 Secondary Structure Analysis and Single-Nucleotide Polymorphism in Ganoderma lucidum

Zhang

Pei

et al. 2017

PLoS ONE

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Ganoderma lucidum is a typical polypore fungus used for traditional Chinese medical purposes. The taxonomic delimitation of Ganoderma lucidum is still debated. In this study, we sequenced seven internal transcribed spacer (ITS) sequences of Ganoderma lucidum strains and annotated the ITS1 and ITS2 regions. Phylogenetic analysis of ITS1 differentiated the strains into three geographic groups. Groups 1–3 were originated from Europe, tropical Asia, and eastern Asia, respectively. While ITS2 could only differentiate the strains into two groups in which Group 2 originated from tropical Asia gathered with Groups 1 and 3 originated from Europe and eastern Asia. By determining the secondary structures of the ITS1 sequences, these three groups exhibited similar structures with a conserved central core and differed helices. While compared to Group 2, Groups 1 and 3 of ITS2 sequences shared similar structures with the difference in helix 4. Large-scale evaluation of ITS1 and ITS2 both exhibited that the majority of subgroups in the same group shared the similar structures. Further Weblogo analysis of ITS1 sequences revealed two main variable regions located in helix 2 in which C/T or A/G substitutions frequently occurred and ITS1 exhibited more nucleotide variances compared to ITS2. ITS1 multi-alignment of seven spawn strains and culture tests indicated that a single-nucleotide polymorphism (SNP) site at position 180 correlated with strain antagonism. The HZ, TK and 203 fusion strains of Ganoderma lucidum had a T at position 180, whereas other strains exhibiting antagonism, including DB, RB, JQ, and YS, had a C. Taken together, compared to ITS2 region, ITS1 region could differentiated Ganoderma lucidum into three geographic originations based on phylogenetic analysis and secondary structure prediction. Besides, a SNP in ITS 1 could delineate Ganoderma lucidum strains at the intraspecific level. These findings will be implemented to improve species quality control in the Ganoderma industry.

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“…The overestimation of gelatinization enthalpy from the DSC method may due to the overlap of the protein denaturation peak (protein from soybean meal or corn) with the starch gelatinization peak. Another potential source of this overestimation may be the relative high quantity of DDGS (30%, wt/wt; Table 1) and a potential conformational change of the polysaccharides in DDGS during DSC measurement (Liu et al, 2014). Moreover, the sugars in DDGS may delay the temperature of starch gelatinization in samples by limiting water availability and decreasing water activity.…”

Section: Methodology Evaluation For Degree Of Starch Gelatinizationmentioning

confidence: 99%

An evaluation of total starch and starch gelatinization methodologies in pelleted animal feed1

Zhu

Jones

Guo

et al. 2016

Journal of Animal Science

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Physicochemical characterization of a high molecular weight bioactive β-d-glucan from the fruiting bodies of Ganoderma lucidum

Cited by 106 publications

References 43 publications

Chitin–glucan complex production by Komagataella pastoris : Downstream optimization and product characterization

Chitin–glucan complex production by Komagataella pastoris : Downstream optimization and product characterization

Intraspecific Variation and Phylogenetic Relationships Are Revealed by ITS1 Secondary Structure Analysis and Single-Nucleotide Polymorphism in Ganoderma lucidum

An evaluation of total starch and starch gelatinization methodologies in pelleted animal feed1

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