2023
DOI: 10.1007/s10930-023-10092-x
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Physicochemical Characterization of a Recombinant eCG and Comparative Studies with PMSG Commercial Preparations

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Cited by 8 publications
(3 citation statements)
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“…Glycoprotein hormones, including hCG, eCG, eFSH, eel FSH, and eel LH, are indicators of the cAMP responses via interactions with those receptors [2,6,43], the ovarian superstimulatory response and embryonic development by rec-eCG [44,45], and the in vivo potency of rec-hCG [46]. Many studies have reported that the biological activity of rec-glycoprotein hormones is dramatically reduced by deglycosylation at the specific glycosylation sites [46][47][48][49].…”
Section: Discussionmentioning
confidence: 99%
“…Glycoprotein hormones, including hCG, eCG, eFSH, eel FSH, and eel LH, are indicators of the cAMP responses via interactions with those receptors [2,6,43], the ovarian superstimulatory response and embryonic development by rec-eCG [44,45], and the in vivo potency of rec-hCG [46]. Many studies have reported that the biological activity of rec-glycoprotein hormones is dramatically reduced by deglycosylation at the specific glycosylation sites [46][47][48][49].…”
Section: Discussionmentioning
confidence: 99%
“…CHO DG44 cells are reported to be a good model for producing large quantities of rec-therapeutic proteins, such as erythropoietin [ 49 ], α-thrombin [ 50 ], alpha-1 antitrypsin [ 51 ], hFSH [ 52 ], hCG [ 53 ], and eLH/CG [ 54 , 55 ]. The Japanese eel is one of the most important fish species in East Asian countries.…”
Section: Introductionmentioning
confidence: 99%
“…CHO DG44 cells are reported to be a good model for producing large quantities of rectherapeutic proteins, such as erythropoietin [49], α-thrombin [50], alpha-1 antitrypsin [51], hFSH [52], hCG [53], and eCG [54,55]. Japanese eel is one of the most important fish species in East Asian countries.…”
Section: Introductionmentioning
confidence: 99%