Physicochemical characterization of Ayurvedic bhasma (Swarna makshika bhasma): An approach to standardization

Mohaptra, Sudhaldev; Jha, Chandra Bhushan

doi:10.4103/0974-7788.64409

Cited by 45 publications

(39 citation statements)

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“…The XRD pattern of SL shows the presence of Fe 2 O 3 (maghamite) as the major phase, which is marked to the corresponding peak of each phase and remaining peaks of CuS, FeS 2 were minor phases. The presence of Fe 2 O 3 (maghamite) in Lauha bhasma, CuS peaks along with FeS 2 peaks in Swarna Makshika bhasma were reported by the earlier scholars 9 . XRD study also confirmed that absence of any free metal in SL.…”

Section: Discussionmentioning

confidence: 51%

“…Reduction in particle size indicates the proper preparation of bhasma and is responsible for high biological activities of these metals and minerals derived substances. It also facilitates absorption and assimilation of the bhasma in the system 9 . The particle size ranges from < 2 to 20 μ and the bigger particles were agglomeration of smaller particles itself.…”

Section: Discussionmentioning

confidence: 99%

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Characterization of an Ayurvedic Drug (Shilajatwadi Lauha): An Approach to Standardization

Singh¹,

Gupta²,

Kumar³

et al. 2014

Int. J. Res. Ayurveda Pharm.

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Shilajatwadi Lauha (SL) is an Ayurvedic Herbo mineral compound formulation used in the treatment of Kshaya and Madhumeha from ancient times. The present study was selected to standardize SL which can be adopted by different Ayurvedic pharmacies for its standardization. For preparation of SL pure Shilajit, Swarna Makshik Bhasma, Shunthi-Marich-Pippali Churna (Trikatu) were taken in equal quantity in mortar and pestle and six times of Lauha Bhasma were added in it and triturated until it becomes fine powder and homogenously mixed. Each of the ingredients was prepared according to the protocols of Ayurvedic texts and by applying Electric muffle furnace as heating device for incineration. To ensure the proper preparation of Bhasmas and other ingredients bhasma parikshas and other tests were employed. After completion of all tests, SL was prepared and subjected for XRD and SEM analysis. XRD study reveals that strongest peak obtained was Fe2O3 and other identified compound was CuS and FeS2 and SEM study shows that the particle size of SL was between 2 to 20 µm. This is the first study in establishing the characterization of SL.

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Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 99%

Characterization of an Ayurvedic Drug (Shilajatwadi Lauha): An Approach to Standardization

Singh¹,

Gupta²,

Kumar³

et al. 2014

Int. J. Res. Ayurveda Pharm.

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“…The process was repeated using Shuddha Gandhaka in equal proportion to Swarna makshika for the first cycle and then in half the proportion for subsequent 8 cycles. Bhasma of the desired quality was obtained from the above process 32 .…”

Section: Preparation Of Swarna Makshika Bhasmamentioning

confidence: 99%

Untitled

2018

IJPSR

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ABSTRACT:With the advent of nanotechnology, it has become important to realize the immense potential of ayurvedic bhasma which had been there for centuries. The study of ayurvedic bhasma as nanomedicine is an important interdisciplinary research area in need of contributions from material science, chemistry, pharmacology, etc. Such a research will definitely help in the characterization and standardization of these bhasmas which is a very complex problem. However, this system is not getting recognition in other parts of the world. Among the various reasons listed for lack of popularity of ayurveda, is non-availability of 'standards' for ayurvedic medicine particularly when prepared on large scale in modern pharmaceutical plants, matching the convenience palatability of modern dosage forms. Many times, it is reported that the preparation, particularly those mineral based are found to contain toxic substances exceeding permissible limits. There has been a lot of hue and cry regarding the safety and efficacy of the bhasmas, especially after publication of certain reports in print media. Further, the commercial pharmacies not adhering to the traditional methods adopt short cut methods and use of adulterated / substandard material augmented the apprehensions in public over their utility. It is therefore needed to explore the same with a multidisciplinary approach, the present study is contemplated. The present review is aimed at finding out the ways and means to standardize the manufacturing processes and develop standardization methods after they have been formed.

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“…It is also used in various medicinal traditions to treat various diseases. Honey has been reported to be as an anti-microbial agent, [11] effective in gastrointestinal disorders, in healing of wounds and burns, and to provide gastric protection against acute and chronic gastric lesions. [12] Another vehicle used in this formulation is ghee.…”

Section: Introductionmentioning

confidence: 99%

Preparation and screening of Swarnaprashana for nootropic activity

Warad¹,

Shastri²,

Habbu³

et al. 2014

Int J Nutr Pharmacol Neurol Dis

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Context: Cognitive disorders are responsible for memory impairments, deterioration of language, motor, sensory abnormalities, gait disturbance, and seizures. Nootropic agents are being primarily used to improve memory, mood and behavior. Aims: In the present study, it was aimed to prepare and evaluate the traditional formulation, Swarnaprashana for its nootropic efficacy on the learning and memory by employing exteroceptive and interoceptive behavioral models in young and aged mice. Settings and Design: In the present study, Swarnaprashana (30 mg/kg, p.o.) was administered to young and aged Swiss albino mice for 15 days. The elevated plus-maze and Morris water maze were used as exteroceptive behavior models. Materials and Methods: Swarnaprashana was prepared by mixing Swarnabhasma (gold) with honey and ghee was used as vehicle. Scopolamine and naturally ageing-induced amnesic models were used as interoceptive behavior models. Biochemical parameter such as whole brain acetylcholinesterase (AChE) activity is used to quantify the nootropic activity. Piracetam (200 mg/kg, p.o.) was used as a standard nootropic agent. Statistical Analysis Used: All data were expressed as mean ± standard error of the mean of 6 mice/experimental group. Parametric one-way analysis of variance followed by Tukey's posttest. Statistical analyses were performed using Graph pad prism 5.0. The minimal level of significance was identified at P < 0.05. Results: The pretreatment of Swarnaprashana (30 mg/kg, p.o.) exhibited significant improvement in learning and memory (P < 0.01) and also showed significant (P < 0.001) decrease in whole brain AChE activity. Conclusions: The present findings suggest that formulation Swaranaprashana has nootropic and anti-AChE activity. Hence, it can be employed in enhancing the memory of the child and for the treatment and management of Alzheimer's disease. Optimized content for mobile and hand-held devicesHTML pages have been optimized for mobile and other hand-held devices (such as iPad, Kindle, iPod) for faster browsing speed. Click on [Mobile Full text] from Table of Contents page. This is simple HTML version for faster download on mobiles (if viewed on desktop, it will be automatically redirected to full HTML version)

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Physicochemical characterization of Ayurvedic bhasma (Swarna makshika bhasma): An approach to standardization

Cited by 45 publications

References 1 publication

Characterization of an Ayurvedic Drug (Shilajatwadi Lauha): An Approach to Standardization

Characterization of an Ayurvedic Drug (Shilajatwadi Lauha): An Approach to Standardization

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Preparation and screening of Swarnaprashana for nootropic activity

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