Physicochemical parameters and thermodynamic behavior of aprepitant/HS15 micellar system at different temperatures: Effect of electrolytes concentration

Kong, Haiting; Li, Yiqi; Wang, Duo; Liang, Hong; Pan, Hongchun

doi:10.1016/j.molliq.2021.115343

Cited by 7 publications

(2 citation statements)

References 48 publications

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“…Which in turn leads to an increase in the diffusion movement of the drug inside the solution and the presence of the surface-active substance, which increases the growth of filamentous micelles of the solution, as shown in Figure (9- The mixture of sodium dodecyl benzene sulfonate (SDBS) negative ionic surfactant with the drug shows an increase in the dynamic viscosity curve and the ratio of 2/8 indicates the formation of wormy micelles. The results show that the presence of the benzene ring in SDBS causes a bad product towards the formation of the unidirectional assembly in contrast to what was previously studied [29][30]. The reason for this is also due to the nature of the surfactant, in addition to the presence of the ion accompanying the surfactant, which is bromide and also to the hydrophobic effect.…”

Section: Resultscontrasting

confidence: 60%

“…The relationship between ln η and the reciprocal of temperature 1/T was drawn to extract the value of ∆H from the slope. The change in the enthalpy sign indicates that the micellization process is exothermic [29,32], and a negative ∆G˚ value is noted, indicating that the process is spontaneous, And the ˚∆S is negative because the micellization process is random [30] (Table 3).…”

Section: Resultsmentioning

confidence: 99%

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Studying the effect of gold nanoparticles on mixture of surfactant of sodium dodecyl benzene sulfonate (SDBS) surfactant and folic acid

Alwan

Jebur

2021

Egypt. J. Chem.

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Gold nanoparticles were prepared from yeast dough via gold salt reduction and their effect on rheology of a mixture of folic acid and the surfactant of sodium dodecyl benzene sulfonate (SDBS) was studied. The results revealed that the highest viscosity (pa. s7.1232×10 2 ) was at a ratio of 2/8, a temperature of 10 o C and a concentration of 0.00004M of nano-gold. So, micelles growth is occurred by increasing nano-gold concentration. In the same manner, measuring the conductivity of the prepared solution revealed that there is a reverse proportion between conductivity and viscosity. Also, thermodynamic functions were calculated such as standard free energy (ΔGº), standard enthalpy (ΔH) and standard entropy (ΔSº) for the formed micelles together with calculating the micellization activation energy. Gold nanoparticles were prepared from yeast dough (Saccharomyces cerevisiae), via gold salt reduction, and the prepared nanoparticles were diagnosed by several techniques (UV-Vis.,x-ray, TEM, SEM), through which the results showed that the prepared gold particles have a purple colour at length (552nm) it has a spherical shape and is within the nano size that was specified by the Shearer equation. The effect of these prepared nanoparticles on the rheology of the mixture of folic acid and the surfactant of Sodium Dodecyl Benzene sulfonate was studied using different temperatures, as this study showed that the highest viscosity Its value was (pa. s7.1232×10 2) at the ratio (2/8) and at a temperature of 10C o and when the concentration of nano-gold was 0.00004M. If these results indicate that the growth of micelles increases with the increase in the concentration of the prepared nano-gold. The conductivity measurement of the solutions prepared for the mixture was also studied, as it was found that the conductivity increases as the viscosity decreases in the presence of nano-gold particles, which leads to an increase in the growth of micelles. From calculating the thermodynamic functions, it was found that the standard free energy (ΔGº) is negative, the standard enthalpy (ΔH) is negative and the standard entropy (ΔSº) is negative for the formed micelles.

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Section: Resultscontrasting

confidence: 60%

Section: Resultsmentioning

confidence: 99%

Studying the effect of gold nanoparticles on mixture of surfactant of sodium dodecyl benzene sulfonate (SDBS) surfactant and folic acid

Alwan

Jebur

2021

Egypt. J. Chem.

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Glucose‐induced self‐assembly in structurally diverse polyoxyethylene based nonionic surfactants for enhanced anticancer drug solubilization

Kuperkar,

Prajapati,

Marangoni

et al. 2024

J Surfact & Detergents

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This study investigates the influence of glucose in inducing the micellar growth/transition in several structurally diverse, longer, and shorter chain polyoxyethylene (POE)‐based nonionic surfactants, commercially known as Kolliphor® HS15 (Solutol), Kolliphor EL®, Akypo®, Brij®‐78, Pluronic® (P103 and F77), Tetronic® (T1304), and Tyloxapol® in aqueous solution environment. It was observed that the addition of glucose induces dehydration of the POE moieties or chains in the tested systems, thereby enhancing the inter‐micellar interactions via hydrogen bonding in the hydrophilic part of the selected surfactants. This dehydration leads to an interesting clouding behavior across all the studied surfactant systems. Also, the dynamic light scattering (DLS) technique accounted for the probable self‐assembly and micellar growth in water and 1 M glucose (fix) across various temperatures. Being pharmaceutical excipients, these micellar entities were successfully employed to assay the hydrophobic anticancer drug curcumin (Cur) solubilized, as confirmed by the peak intensity variation from UV–visible spectroscopy. Cur solubilization into glucose‐containing micelles revealed enhanced solubility expressed in terms of drug loading efficiency (DL%), encapsulation efficiency (EE%), partition coefficient (log P), and standard free energy of solubilization (ΔG°), which is due to the glucose‐induced hydrophobicity in the examined nonionic micellar systems.

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Development and optimization of aprepitant/HS15/TW80 composite system: Based on micellization thermodynamics

Wang

Kong³

et al. 2022

Journal of Molecular Liquids

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Physicochemical parameters and thermodynamic behavior of aprepitant/HS15 micellar system at different temperatures: Effect of electrolytes concentration

Cited by 7 publications

References 48 publications

Studying the effect of gold nanoparticles on mixture of surfactant of sodium dodecyl benzene sulfonate (SDBS) surfactant and folic acid

Studying the effect of gold nanoparticles on mixture of surfactant of sodium dodecyl benzene sulfonate (SDBS) surfactant and folic acid

Glucose‐induced self‐assembly in structurally diverse polyoxyethylene based nonionic surfactants for enhanced anticancer drug solubilization

Development and optimization of aprepitant/HS15/TW80 composite system: Based on micellization thermodynamics

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