Physics Models of Pronuclear Movements in Eggs

Abstract

Based on published experimental data, Newton's laws, and Coulomb's law, we investigate natural and normal pronuclear movements in wild types of eggs and develop physics models to fit the experimental data quantitatively. The difference between our modeling calculated results and the experimental data is less than 20%. Our models explain why and how pronuclei move in even or in variant velocities. We hypothesize: During the migration, positively charged asters (or self assembled microtubules) drive two negatively charged sperm and egg pronuclei to move towards each other. The driving force comes from a spontaneous and strong Electromagnetic Field (EMF). Hamilton's principle determines the path of these movements. A natural and normal EMF inside or around the pronuclei can be alternated environmentally. An abnormal EMF could induce aberrant embryos that cause life disease. We believe our models are helpful to further understand the mechanism of fertilization and have potential clinical value to prevent aberrant embryos that induce human life disease.

Informatics and Physics Models of Recognitions of DNA Replication and Their Biological Applications

“…The protoplasm has been considered as an electrolyte with an uneven charge distribution and the natural cellular electric field has been considered as quasi static [12][13][14][15][16] . We use the same consideration to propose our new models of an informative recognition between an initiation site (a sender of information) for a natural DNA replication and a DNA polymerase (a receiver of information) beyond lengths of chemical bounds (Fig.…”