The paper addresses basic features of non-axisymmetric edge transport induced in tokamaks by local limiters or external magnetic perturbations and in low-shear stellarators by the presence of edge magnetic islands. 3D simulations and, if available for comparison, experimental results are presented and discussed for three devices, ITER during start-up operation, TEXTOR-DED and W7-AS, having edge topologies totally different from each other. The modeling is performed with the EMC3/EIRENE code, which treats self-consistently plasma, neutral and impurity transport in a general 3D Scrape-Off Layer (SOL) with arbitrarily complex geometry of magnetic configuration and plasma-facing components. Shown are code predictions of the power load on the ITER start-up limiters as well as modeling results on the transport in the TEXTOR-DED stochastic edge and on the physics of stable detachment in W7-AS. Experimental observations confirming the code simulations are referenced for both TEXTOR-DED and W7-AS, a direct comparison between modeling and experimental results is shown for W7-AS.