Physio-Chemical Properties and Dielectric Behavior of As-Grown Manganese Oxide (γ-Mn2O3) Nanoparticles

Abdullah, M.M.; Siddiqui, Sahabjada; Al-Abbas, Saleh M.

doi:10.1007/s11664-020-08171-1

Cited by 13 publications

(5 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Methodsmentioning

confidence: 99%

“…The sample powder was placed with the help of double-sided adhesive glue provided with conductive gold coating. The elemental compositions of the developed formulation as a drug-loaded delivery system were further confirmed by the energy-dispersive X-ray spectroscopy (EDS) [24]. The 3D printed drug-loaded self-nanoemulsifying tablet was dispersed in distilled water and characterized to determine the droplet size, polydispersity index (PdI), and zeta potential (ξ) by dynamic light scattering technique using Zetasizer (Malvern Instruments Ltd., Malvern, UK) at room temperature.…”

Section: Surface Morphology By Scanning Electron Microscopy (Sem)mentioning

confidence: 99%

See 1 more Smart Citation

3D Printing of Dapagliflozin Containing Self-Nanoemulsifying Tablets: Formulation Design and In Vitro Characterization

et al. 2021

Self Cite

View full text Add to dashboard Cite

The 3D printing techniques have been explored extensively in recent years for pharmaceutical manufacturing and drug delivery applications. The current investigation aims to explore 3D printing for the design and development of a nanomedicine-based oral solid dosage form of a poorly water-soluble drug. A self-nanoemulsifying tablet formulation of dapagliflozin propanediol monohydrate was developed utilizing the semisolid pressure-assisted microsyringe (PAM) extrusion-based 3D printing technique. The developed formulation system consists of two major components (liquid and solid phase), which include oils (caproyl 90, octanoic acid) and co-surfactant (PEG 400) as liquid phase while surfactant (poloxamer 188) and solid matrix (PEG 6000) as solid-phase excipients that ultimately self-nanoemulsify as a drug encapsulated nanoemulsion system on contact with aqueous phase/gastrointestinal fluid. The droplet size distribution of the generated nanoemulsion from a self-nanoemulsifying 3D printed tablet was observed to be 104.7 ± 3.36 nm with polydispersity index 0.063 ± 0.024. The FT-IR analysis of the printed tablet revealed that no drug-excipients interactions were observed. The DSC and X-RD analysis of the printed tablet revealed that the loaded drug is molecularly dispersed in the crystal lattice of the tablet solid matrix and remains solubilized in the liquid phase of the printed tablet. SEM image of the drug-loaded self-nanoemulsifying tablets revealed that dapagliflozin propanediol monohydrate was completely encapsulated in the solid matrix of the printed tablet, which was further confirmed by SEM-EDS analysis. The in vitro dissolution profile of dapagliflozin-loaded self-nanoemulsifying tablet revealed an immediate-release drug profile for all three sizes (8 mm, 10 mm, and 12 mm) tablets, exhibiting >75.0% drug release within 20 min. Thus, this study has emphasized the capability of the PAM-based 3D printing technique to print a self-nanoemulsifying tablet dosage form with an immediate-release drug profile for poorly water-soluble drug.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Surface Morphology By Scanning Electron Microscopy (Sem)mentioning

confidence: 99%

3D Printing of Dapagliflozin Containing Self-Nanoemulsifying Tablets: Formulation Design and In Vitro Characterization

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…Synthetic manganese oxides and manganese oxide minerals play an important role in different technological processes and applications. , For example, some of them are utilized as effective catalysts, − as supercapacitors, as ferroelectrics or multiferroics, − as elements in ion batteries, − as semiconductors, and for many other purposes. − In general, manganese oxides, including Mn-based perovskites, − are inexpensive and highly functional materials, which combine interesting electronic and magnetic properties and, therefore, have remained in the focus of recent investigations.…”

Section: Introductionmentioning

confidence: 99%

Structural Stability and Properties of Marokite-Type γ-Mn₃O₄

et al. 2021

View full text Add to dashboard Cite

We synthesized single crystals of marokite (CaMn2O4)-type orthorhombic manganese (II,III) oxide, γ-Mn3O4, in a multianvil apparatus at pressures of 10–24 GPa. The magnetic, electronic, and optical properties of the crystals were investigated at ambient pressure. It was found that γ-Mn3O4 is a semiconductor with an indirect band gap E g of 0.96 eV and two antiferromagnetic transitions (T N) at ∼200 and ∼55 K. The phase stability of the γ-Mn3O4 crystals was examined in the pressure range of 0–60 GPa using single-crystal X-ray diffraction and Raman spectroscopy. A bulk modulus of γ-Mn3O4 was determined to be B 0 = 235.3(2) GPa with B′ = 2.6(6). The γ-Mn3O4 phase persisted over the whole pressure range studied and did not transform or decompose upon laser heating of the sample to ∼3500 K at 60 GPa. This result seems surprising, given the high-pressure structural diversity of iron oxides with similar stoichiometries. With an increase in pressure, the degree of distortion of MnO6 polyhedra decreased. Furthermore, there are signs indicating a limited charge transfer between the Mn3+ ions in the octahedra and the Mn2+ ions in the trigonal prisms. Our results demonstrate that the high-pressure behavior of the structural, electronic, and chemical properties of manganese oxides strongly differs from that of iron oxides with similar stoichiometries.

show abstract

“…The band observed at ∼ 600, and 770 cm -1 indicate the presence of the bending vibrations of Al-O-Al, and Al-O band, respectively. Whereas, the two other bands at 1625 and 3453 cm -1 shows the -OH stretching vibrations (Abdullah et al, 2020;Saif A. Naayi et al, 2018;Sathiya Narayanan et al, 2019). These band are due to the physiosorbed water molecule, that was captured by the material during pellet preparation.…”

Section: Resultsmentioning

confidence: 99%

Dielectric spectroscopy of aluminum oxide (γ-Al2O3)

Abdullah

2021

KJS publishes peer-review articles in Mathematics, Computer Sci

Self Cite

View full text Add to dashboard Cite

Aluminum oxide (Al2O3) are continuously demonstrating the functional characteristics in devices. The physiochemical properties of hydrothermally as-grown Aluminum oxide (Al2O3) have been investigated in this research article. The as-prepared material was confirmed as γ- phase formation of Al2O3. The average crystallite size was found ∼ 78 nm, whereas the particles were found in nano scale too. Moreover, the absence of impurity in EDS analysis, and the presence of the bending vibrations of Al-O-Al and Al-O band in FTIR characterization further confirmed the absence of impurity in the material. Evaluated dielectric properties such as a relatively high dielectric constant, and low dielectric loss indicated the good optical quality of γ- Al2O3. Impedance and modulus spectroscopic studies showed the non-Debye type relaxation in γ- Al2O3 with an average relaxation time of 5.8 μs. Overall, the dielectric spectroscopy analysis of γ- Al2O3 indicates the promising applications of γ- Al2O3 in devices as dielectrics.

show abstract

Physio-Chemical Properties and Dielectric Behavior of As-Grown Manganese Oxide (γ-Mn2O3) Nanoparticles

Cited by 13 publications

References 46 publications

3D Printing of Dapagliflozin Containing Self-Nanoemulsifying Tablets: Formulation Design and In Vitro Characterization

3D Printing of Dapagliflozin Containing Self-Nanoemulsifying Tablets: Formulation Design and In Vitro Characterization

Structural Stability and Properties of Marokite-Type γ-Mn₃O₄

Dielectric spectroscopy of aluminum oxide (γ-Al2O3)

Contact Info

Product

Resources

About

Physio-Chemical Properties and Dielectric Behavior of As-Grown Manganese Oxide (γ-Mn2O3) Nanoparticles

Cited by 13 publications

References 46 publications

3D Printing of Dapagliflozin Containing Self-Nanoemulsifying Tablets: Formulation Design and In Vitro Characterization

3D Printing of Dapagliflozin Containing Self-Nanoemulsifying Tablets: Formulation Design and In Vitro Characterization

Structural Stability and Properties of Marokite-Type γ-Mn3O4

Dielectric spectroscopy of aluminum oxide (γ-Al2O3)

Contact Info

Product

Resources

About

Structural Stability and Properties of Marokite-Type γ-Mn₃O₄