Physiological advantages of children against COVID‐19

Yavuz, Sinan; Kesici, Selman; Bayrakçı, Benan

doi:10.1111/apa.15410

Cited by 11 publications

(8 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…First, the ACE2-positive cells were scattered in the neonatal rat lungs, while they were extensively detected in adult rat lungs (Figure 1), We also found that neonatal pups had fewer AT2 cells (SPC-positive) compared to adult rats (Figure 2), which was consistent with the ACE2 expression in human lungs in other studies [7,18,19]. However, Zhang et al reported ACE2+ cells were extensively stained in lung biopsies from young patients while few were observed in elder patients with COVID-19 [14].…”

Section: Discussionsupporting

confidence: 88%

Pulmonary ACE2 expression in neonatal and adult rats

et al. 2021

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 88%

Pulmonary ACE2 expression in neonatal and adult rats

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Until recently, the clinical course of coronavirus disease (COVID-19) has been reported as mild in children [ 1 , 2 ]. However, some children with COVID-19 have become critically ill and this illness is now termed multisystem inflammatory syndrome in children (MIS-C), or pediatric multisystem inflammatory syndrome (PMIS) [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

A Case of Multisystem Inflammatory Syndrome in Children Mimicking Acute Appendicitis in a COVID-19 Pandemic Area

Jackson¹,

Chavarria²,

Hacking³

2020

Cureus

View full text Add to dashboard Cite

The outbreak of the novel coronavirus (2019-nCoV) began in Wuhan, China and spread rapidly throughout the world. As of now, there have been numerous reports demonstrating clinical, radiological and pathological findings in adults. In children, the disease has essentially been seen as mild and self-limiting. However, more recently, children have been presenting with findings reminiscent of Kawasaki’s disease. And secondary to this, the benign nature of COVID-19 disease in children is beginning to be challenged. This phenomenon is now referred to as multisystem inflammatory syndrome in children (MIS-C). Further understanding the clinical course in MIS-C and its temporal association with coronavirus disease 2019 will be paramount for treatment and public health decision making. This correspondence describes a case of MIS-C with gastrointestinal manifestations mimicking acute appendicitis in a child presenting from a COVID-19 endemic area.

show abstract

“…Possible explanations for the milder courses in children include a not yet fully developed angiotensin converting enzyme (ACE), partial cross-immunity from other respiratory corona viruses and possibly a better alveolar clearance in children [ 14 ], [ 15 ], [ 16 ], [ 17 ], [ 18 ].…”

Section: Introductionmentioning

confidence: 99%