The potential of encapsulated calcium carbide (ECC) in improving growth, yield and physiology of cotton under salinity was evaluated in pot experiment. Salinity was induced by sodium chloride (NaCl) @ 0, 1250 and 2000 ppm. The ECC was applied at the rate of 0, 15, and 30 mg kg -1 soil. The results revealed that ECC improved number of branches, yield, shoot dry biomass, root dry biomass, by 57, 67, 40, 22, and 18% respectively, over control. Similarly, net photosynthesis, stomatal conductance nitrogen, phosphorus and potassium (N, P and K) Downloaded by [Texas A & M International University] at 21:40 16 August 2015 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 2 concentration of shoot were enhanced by 38, 34, 7, 25 and 11% over control, respectively. The induction of new set of proteins ranging from 11 to 26 kDa was also observed at various levels of ECC and salinity stress. These results proved the efficacy of very lower concentrations of ethylene produced by ECC and showed the behavior of different parameters of cotton to it under saline stress.