Physiological and transcriptomic responses of Chlorella sorokiniana to ciprofloxacin reveal molecular mechanisms for antibiotic removal

Li, Zhuo; Li, Shuangxi; Li, Tianrui; Gao, Xinxin; Zhu, Linna

doi:10.1016/j.isci.2022.104638

Cited by 14 publications

(1 citation statement)

References 72 publications

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“…The mode of uptake/remediation remains to be confirmed and further experimentation is required to optimise and further understand algal interactions in a wastewater environment. However, studies on the uptake of ciprofloxacin by a Chlorella isolate found degradation through oxidoreductases to be one of the mechanisms employed by microalgae, in addition to releasing humic substances to prevent damage at concentrations of up to 20 mg/L [ 43 ]. In addition, the removal of persistent levofloxacin was recorded in Chlorella vulgaris , up to 11% over a similar period of 11 days.…”

Section: Discussionmentioning

confidence: 99%

Removal of Antibiotics Using an Algae-Algae Consortium (Chlorella protothecoides and Chlorella vulgaris)

Ndlela

Schröder

Genthe

et al. 2023

Toxics

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The intensive use of antibiotics (for human, veterinary, and agricultural purposes) has steadily increased over the last 30 years. Large amounts of antibiotic residues are released into aquatic systems, mostly due to inefficient wastewater treatment. Conventional wastewater treatments are not designed to remove emerging contaminants (such as antibiotics) from wastewater. Therefore, algae treatment (phycoremediation) has emerged as a promising choice for cost-effective, eco-friendly, and sustainable wastewater treatment. For this reason, we investigated the removal performance of a well-established algal consortia (Chlorella protothecoides and Chlorella vulgaris) used in passive wastewater treatment ponds (Mosselbay, South Africa). Five antibiotics (sulfamethoxazole, amoxicillin, trimethoprim, ofloxacin, and clarithromycin) were selected for their ubiquity and/or low removal efficiency in conventional wastewater treatment plants (WWTPs). For each antibiotic, two concentrations were used: one environmentally relevant (10 ppb) and another 10 times higher (100 ppb), tested in triplicate and collected at two-time points (7 and 10 days). The algae remained viable over the exposure period (which is similar to the retention time within maturation ponds) and exhibited the capacity to remove sulfamethoxazole (77.3% ± 3.0 and 46.5% ± 5.3) and ofloxacin (43.5% ± 18.9 and 55.1% ± 12.0) from samples spiked with 10 and 100 ppb, respectively. This study demonstrates the potential and innovation of algal remediation for contaminants in a developing country context, where minimal infrastructure is available.

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Section: Discussionmentioning

confidence: 99%