Physiological Chemistry of the Eye

Dische, Zacharias

doi:10.1001/archopht.1956.00930040595008

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) Mode Of Inhibitory Action Of Iodoacetate1

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1958

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“…To identify with certainty the precise mechanism responsible for this lethal change is no easy task with so versatile an inhibitor as iodoacetate. Noell's original hypothesis that it acts by exerting a simple selective 536 EFFECTS OF THIOL REAGENTS ON RETINA blocking action upon visual cell glycolysis has been questioned by Dische (1953Dische ( , 1956 and Wald (1955), and the present work does little to confirm Noell's view. That glycolysis is depressed very soon after injection is certainly true.…”

Section: ) Mode Of Inhibitory Action Of Iodoacetatecontrasting

confidence: 56%