2002
DOI: 10.1186/cc1498
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Physiological-dose steroid therapy in sepsis [ISRCTN36253388]

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Cited by 148 publications
(38 citation statements)
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References 43 publications
(34 reference statements)
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“…2). Consistent with our previous analysis, heterogeneity decreased when the 21 trials were partitioned into studies published before 1989 [24,25,27,30–35] and published after 1997 [8,17–23,26,28,29,36]. As the group of trials published before 1989 was identical to our previous analysis, they were analysed in a similar fashion, with subsequent exclusion of a single outlier study from subsequent analyses (Fig.…”
Section: Resultssupporting
confidence: 78%
See 2 more Smart Citations
“…2). Consistent with our previous analysis, heterogeneity decreased when the 21 trials were partitioned into studies published before 1989 [24,25,27,30–35] and published after 1997 [8,17–23,26,28,29,36]. As the group of trials published before 1989 was identical to our previous analysis, they were analysed in a similar fashion, with subsequent exclusion of a single outlier study from subsequent analyses (Fig.…”
Section: Resultssupporting
confidence: 78%
“…1) [17–23]. Characteristics of the 21 trials included in this analysis are depicted in Table 1 [8,1736]. All included studies were prospective randomized trials that involved similar co-interventions in each study group, with the exception of the steroid regimen being investigated.…”
Section: Resultsmentioning
confidence: 99%
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“…Three LOE 5 randomized controlled trials in adults with vasopressor-dependent septic shock 457,462,463 showed that survival was improved when low-dose hydrocortisone was administered, while 1 small adult LOE 5 randomized controlled trial 464 showed a trend toward increased survival.…”
Section: Arrhythmia Therapypeds-030mentioning
confidence: 99%
“…The odds of mortality (four studies [8,36,42,45]), for both corticotrophin responders and non-responders was not significantly different compared with control (Table 5). …”
Section: Resultsmentioning
confidence: 99%